电针对腹腔镜胆囊手术患者颈内动脉血流的影响：随机临床试验

IF 2.8 4区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

Integrative Medicine Research Pub Date : 2024-11-02 DOI:10.1016/j.imr.2024.101097

Lili Hu , Yongyan Zhang , Ying Li , Ruiping Wang , Hua Xu

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引用次数: 0

摘要

背景人们对电针（EA）对脑血流的影响知之甚少。我们在接受腹腔镜胆囊切除术的患者中研究了这一问题，假设电针会增加手术中的脑血流量。方法将接受腹腔镜胆囊切除术的 82 名患者随机分为接受电针和静脉麻醉（EA+IA）和单独接受静脉麻醉（IA）。EA+IA患者在麻醉前20分钟在百会穴（GV 20）、水沟穴（GV 26）、单侧内关穴（PC 6）和单侧足三里穴（ST 36）进行电针治疗，直至手术结束。IA患者仅接受静脉麻醉。分别记录麻醉诱导前（T1）、麻醉诱导后2分钟（T2）、气腹后1分钟（T3）、仰头后1分钟（T4）和麻醉复苏后（T5）的颈内动脉血流（Q）、平均动脉压（MAP）、潮气末二氧化碳压力（PETCO2）和心率（HR）。结果在T3和T4，EA+IA的颈内动脉血流（平均值[标度]，T3，294.0 [89.6] ml min-1；T4，303.8 [90.6] ml min-1）明显高于IA（平均值[标度]，T3，246.4 [80.9] ml min-1；T4，253.5 [78.4] ml min-1）（P <0.05）。两组在 T2 和 T5 时的血流量没有差异。与基线（T1）相比，两组颈内动脉血流在 T2-T4 均有所下降（P < 0.05）。结论电针干预可减少腹腔镜胆囊切除术患者颈内动脉血流的下降。

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Effect of electroacupuncture on internal carotid artery blood flow in patients undergoing laparoscopic gallbladder surgery: A randomized clinical trial

Background

Little is known about the effect of electroacupuncture (EA) on cerebral blood flow. We investigated this question in patients undergoing laparoscopic cholecystectomy, hypothesizing that EA would increase cerebral blood flow during surgery.

Methods

Eighty-two patients undergoing laparoscopic cholecystectomy were randomly divided into receiving electroacupuncture and intravenous anesthesia (EA+IA) and receving intravenous anesthesia alone (IA). The patients in EA+IA were treated with EA at Baihui (GV 20), Shuigou (GV 26), unilateral Neiguan (PC 6) and unilateral Zusanli (ST 36) points 20 min before anesthesia until the end of the operation. The patients in IA received intravenous anesthesia alone. The internal carotid artery blood flow (Q), mean arterial pressure (MAP), end-tidal carbon dioxide pressure (P_ETCO₂) and heart rate (HR) were recorded respectively before anesthesia induction (T₁), 2 min after anesthesia induction (T₂), 1 min after pneumoperitoneum (T₃), 1 min after head-up tilt (T₄) and after anesthesia resuscitation (T₅).

Results

The internal carotid artery blood flow was significantly higher in EA+IA (mean [SD], T₃, 294.0 [89.6] ml min^-1; T₄, 303.8 [90.6] ml min^-1) than in IA (mean [SD], T₃, 246.4 [80.9] ml min^-1; T4, 253.5 [78.4] ml min^-1) at T₃ and T₄ (P < 0.05). There was no difference in blood flow between the two groups at T₂ and T₅. As compared with baseline (T₁), the internal carotid artery blood flow decreased at T₂-T₄ in two groups (P < 0.05). There were no differences in MAP, P_ETCO₂, and HR between the two groups.

Conclusion

Electroacupuncture intervention could reduce the decline of internal carotid artery blood flow in patients undergoing laparoscopic cholecystectomy.

Trial registration

ChiCTR: 2,100,041,761.

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来源期刊

Integrative Medicine Research Medicine-Complementary and Alternative Medicine

CiteScore

6.50

自引率

2.90%

发文量

审稿时长

12 weeks

期刊介绍： Integrative Medicine Research (IMR) is a quarterly, peer-reviewed journal focused on scientific research for integrative medicine including traditional medicine (emphasis on acupuncture and herbal medicine), complementary and alternative medicine, and systems medicine. The journal includes papers on basic research, clinical research, methodology, theory, computational analysis and modelling, topical reviews, medical history, education and policy based on physiology, pathology, diagnosis and the systems approach in the field of integrative medicine.