在青光眼治疗中,脂质体局部给药超越了其他方法:一种新型的强化治疗范例。

IF 2.8 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Nor Asyikin Nordin, Muhammad Zulfiqah Sadikan, Lidawani Lambuk, Sabarisah Hashim, Syahira Airuddin, Nur-Azida Mohd Nasir, Rohimah Mohamud, Jamal Ibrahim, Ramlah Kadir
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引用次数: 0

摘要

目标:青光眼是导致永久性失明的主要原因。尽管在治疗方面取得了进展,但由于传统给药方式(主要是局部滴眼液)的局限性,青光眼的治疗仍然面临挑战,导致治疗效果不理想,全球病例激增。为解决这些问题,脂质体给药已成为一种前景广阔的方法:这篇综述探讨了脂质体药物的潜力,特别关注局部用药,与现有治疗方法相比,脂质体药物是提高疗效和改善患者依从性的最佳选择。本文深入探讨了脂质体制剂在不同给药途径中的治疗前景,正在进行的临床试验也证明了这一点。摘要:通过克服眼部障碍和优化给药,脂质体局部给药是显著改善青光眼治疗效果的关键。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Liposomal topical drug administration surpasses alternative methods in glaucoma therapeutics: a novel paradigm for enhanced treatment.

Objectives: Glaucoma is a leading cause of permanent blindness. Despite therapeutic advancements, glaucoma management remains challenging due to limitations of conventional drug delivery, primarily topical eye drops, resulting in suboptimal outcomes and a global surge in cases. To address these issues, liposomal drug delivery has emerged as a promising approach.

Key findings: This review explores the potential of liposomal-based medications, with a particular focus on topical administration as a superior alternative to enhance therapeutic efficacy and improve patient compliance compared to existing treatments. This writing delves into the therapeutic prospects of liposomal formulations across different administration routes, as evidenced by ongoing clinical trials. Additionally, critical aspects of liposomal production and market strategies are discussed herein.

Summary: By overcoming ocular barriers and optimizing drug delivery, liposomal topical administration holds the key to significantly improving glaucoma treatment outcomes.

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来源期刊
CiteScore
6.60
自引率
0.00%
发文量
91
审稿时长
3 months
期刊介绍: JPP keeps pace with new research on how drug action may be optimized by new technologies, and attention is given to understanding and improving drug interactions in the body. At the same time, the journal maintains its established and well-respected core strengths in areas such as pharmaceutics and drug delivery, experimental and clinical pharmacology, biopharmaceutics and drug disposition, and drugs from natural sources. JPP publishes at least one special issue on a topical theme each year.
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