一个严重高胆红素血症和甲状腺毒症的不寻常病例。

Q3 Medicine
Endocrine regulations Pub Date : 2024-11-21 Print Date: 2024-01-01 DOI:10.2478/enr-2024-0025
Mohak Jain, Minal Shastri, Nilay Patel, Riya Dobariya, Abulkalam Sirajwala
{"title":"一个严重高胆红素血症和甲状腺毒症的不寻常病例。","authors":"Mohak Jain, Minal Shastri, Nilay Patel, Riya Dobariya, Abulkalam Sirajwala","doi":"10.2478/enr-2024-0025","DOIUrl":null,"url":null,"abstract":"<p><p><b>Objective.</b> We report a case of a 23-year-old pregnant female with five months of amenorrhea. She was referred to us with rapidly developing jaundice, anemia, and dyspnea with hyperthyroidism. <b>Methods.</b> After initial treatment of all the possible causes of progressive jaundice led to no improvement. The treatment was then heavily directed towards managing thyroid storm. <b>Results.</b> Hepatic dysfunction improved with iodine and thionamides. Patient recovered well. This points towards the uncommon association of severe hyperbilirubinemia with thyroid storm a potentially fatal endocrine disorder and its rapid improvement with iodine and thionamides. <b>Conclusions.</b> Our case suggests that severe hyperbilirubinemia can be caused by hyperthyroidism and the etiology of hepatic dysfunction should include thyrotoxicosis as a probable cause. Aggressive treatment should be done with iodine and thionamides for fruition.</p>","PeriodicalId":11650,"journal":{"name":"Endocrine regulations","volume":"58 1","pages":"215-219"},"PeriodicalIF":0.0000,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"An unusual case of severe hyperbilirubinemia and thyrotoxicosis.\",\"authors\":\"Mohak Jain, Minal Shastri, Nilay Patel, Riya Dobariya, Abulkalam Sirajwala\",\"doi\":\"10.2478/enr-2024-0025\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Objective.</b> We report a case of a 23-year-old pregnant female with five months of amenorrhea. She was referred to us with rapidly developing jaundice, anemia, and dyspnea with hyperthyroidism. <b>Methods.</b> After initial treatment of all the possible causes of progressive jaundice led to no improvement. The treatment was then heavily directed towards managing thyroid storm. <b>Results.</b> Hepatic dysfunction improved with iodine and thionamides. Patient recovered well. This points towards the uncommon association of severe hyperbilirubinemia with thyroid storm a potentially fatal endocrine disorder and its rapid improvement with iodine and thionamides. <b>Conclusions.</b> Our case suggests that severe hyperbilirubinemia can be caused by hyperthyroidism and the etiology of hepatic dysfunction should include thyrotoxicosis as a probable cause. Aggressive treatment should be done with iodine and thionamides for fruition.</p>\",\"PeriodicalId\":11650,\"journal\":{\"name\":\"Endocrine regulations\",\"volume\":\"58 1\",\"pages\":\"215-219\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-11-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Endocrine regulations\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2478/enr-2024-0025\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"Print\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Endocrine regulations","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2478/enr-2024-0025","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"Print","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

目的。我们报告了一例闭经五个月的 23 岁孕妇。她因迅速出现黄疸、贫血和呼吸困难并伴有甲状腺功能亢进症而转诊至我院。治疗方法在对所有可能导致渐进性黄疸的原因进行初步治疗后,情况没有改善。于是,治疗重点转向控制甲状腺风暴。结果。使用碘和硫酰胺类药物后,肝功能异常得到改善。患者恢复良好。这说明严重高胆红素血症与甲状腺风暴这种可能致命的内分泌疾病相关的情况并不常见,而碘和硫酰胺类药物能迅速改善这种情况。结论我们的病例表明,严重的高胆红素血症可由甲状腺功能亢进引起,肝功能异常的病因应包括甲状腺毒症。应使用碘和硫代氨酰胺进行积极治疗,以取得疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An unusual case of severe hyperbilirubinemia and thyrotoxicosis.

Objective. We report a case of a 23-year-old pregnant female with five months of amenorrhea. She was referred to us with rapidly developing jaundice, anemia, and dyspnea with hyperthyroidism. Methods. After initial treatment of all the possible causes of progressive jaundice led to no improvement. The treatment was then heavily directed towards managing thyroid storm. Results. Hepatic dysfunction improved with iodine and thionamides. Patient recovered well. This points towards the uncommon association of severe hyperbilirubinemia with thyroid storm a potentially fatal endocrine disorder and its rapid improvement with iodine and thionamides. Conclusions. Our case suggests that severe hyperbilirubinemia can be caused by hyperthyroidism and the etiology of hepatic dysfunction should include thyrotoxicosis as a probable cause. Aggressive treatment should be done with iodine and thionamides for fruition.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Endocrine regulations
Endocrine regulations Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
2.70
自引率
0.00%
发文量
33
审稿时长
8 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信