变化的媒介：流动遗传因子之间的伙伴关系促进了细菌的快速适应。

IF 14 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Trends in Microbiology Pub Date : 2024-11-19 DOI:10.1016/j.tim.2024.10.010

Elizabeth S Duan, Olivia Kosterlitz, Benjamin Kerr

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引用次数: 0

摘要

虽然移动基因元件的进化利益可能与其细菌宿主的进化利益不同，但这些元件可以通过传递、破坏或激活基因而对宿主有益。萨斯特雷-多明格斯（Sastre-Domínguez）等人最近发表的一篇论文描述了移动基因元件在临床相关细菌中的一种新的协同效应，即携带转座元件的共轭质粒可通过提高转座介导的突变率而成为快速适应性变化的媒介。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Agents of change: a partnership between mobile genetic elements facilitates rapid bacterial adaptation.

While the evolutionary interests of mobile genetic elements may differ from those of their bacterial hosts, these elements can be beneficial for their hosts by delivering, disrupting, or activating genes. A recent paper by Sastre-Domínguez et al. describes a novel synergistic effect of mobile elements in clinically relevant bacteria, whereby conjugative plasmids that carry transposable elements can be agents of rapid adaptive change through an elevation in transposition-mediated mutation rate.

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来源期刊

Trends in Microbiology 生物-生化与分子生物学

CiteScore

25.30

自引率

0.60%

发文量

193

审稿时长

6-12 weeks

期刊介绍： Trends in Microbiology serves as a comprehensive, multidisciplinary forum for discussing various aspects of microbiology, spanning cell biology, immunology, genetics, evolution, virology, bacteriology, protozoology, and mycology. In the rapidly evolving field of microbiology, technological advancements, especially in genome sequencing, impact prokaryote biology from pathogens to extremophiles, influencing developments in drugs, vaccines, and industrial enzyme research.