一名心脏移植受者移植后淋巴增生性疾病复发的动态表现：罕见病例研究。

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2024-11-20 eCollection Date: 2024-11-01 DOI:10.14309/crj.0000000000001554

Avi Toiv, Kevin B Harris, Muhammad Zarrar Khan, Brian K Theisen, Adarsh Varma, Christopher Fain, Nirmal Kaur

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引用次数: 0

摘要

移植后淋巴组织增生性疾病（PTLD）是移植后免疫抑制治疗引起的并发症。虽然 Epstein-Barr 病毒（EBV）病毒血症经常出现在 PTLD 中，但它并不是诊断的明确特征。我们报告了一例罕见的复发性 PTLD 病例，患者 26 岁，接受大剂量他克莫司治疗，出现呕吐、乏力和血性腹泻。虽然在第一次PTLD发作时出现了大量EB病毒感染，但这次是胃肠道表现，几乎检测不到循环中的EB病毒。患者的胃肠道疾病史延误了明确诊断，后来通过内窥镜检查和活检样本分析才确定了诊断。

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Dynamic Presentations of Recurrent Post-Transplant Lymphoproliferative Disorder in a Heart Transplant Recipient: A Rare Case Study.

Post-transplant lymphoproliferative disorders (PTLD) are complications that arise from post-transplantation immunosuppressive therapy. Although Epstein-Barr virus (EBV) viremia is often seen in PTLD, it is not a definitive feature for diagnosis. We report a rare case of recurrent PTLD in a 26-year-old heart transplant recipient on high-dose tacrolimus who presented with emesis, fatigue, and bloody diarrhea. Although substantial EBV viremia was seen in the first PTLD episode, the current episode was a gastrointestinal manifestation with barely detectable circulating EBV. The patient's history of gastrointestinal disease delayed definitive diagnosis, which was later established through endoscopy and biopsy sample analysis.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.