Damsel：用 R 进行 DamID 测序的分析和可视化。

Bioinformatics (Oxford, England) Pub Date : 2024-11-18 DOI:10.1093/bioinformatics/btae695

Caitlin G Page, Andrew Londsdale, Katrina A Mitchell, Jan Schröder, Kieran F Harvey, Alicia Oshlack

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引用次数: 0

摘要

摘要：DamID 测序是一种绘制蛋白质与 DNA 的全基因组相互作用图谱的技术。Damsel 可对重要的结合位点进行量化和测试，并可进行探索性和可视化分析。Damsel 得出的结果与之前的分析方法一致：R软件包Damsel可通过Bioconductor项目 https://bioconductor.org/packages/release/bioc/html/Damsel.html 安装，代码可在GitHub https://github.com/Oshlack/Damsel/.Supplementary 获取：补充数据可在 Bioinformatics online 上获取。

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Damsel: Analysis and visualisation of DamID sequencing in R.

Summary: DamID sequencing is a technique to map the genome-wide interaction of a protein with DNA. Damsel is the first Bioconductor package to provide an end to end analysis for DamID sequencing data within R. Damsel performs quantification and testing of significant binding sites along with exploratory and visual analysis. Damsel produces results consistent with previous analysis approaches.

Availability: The R package Damsel is available for install through the Bioconductor project https://bioconductor.org/packages/release/bioc/html/Damsel.html and the code is available on GitHub https://github.com/Oshlack/Damsel/.

Supplementary information: Supplementary data are available at Bioinformatics online.

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Bioinformatics (Oxford, England)

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