{"title":"一只狗静脉注射甘露醇后出现疑似过敏性反应。","authors":"Kathleen Seddon BSc, BVSc, Georgina Stewart BVSc, DACVIM, Íde Gillespie BVMS, DACVECC","doi":"10.1111/vec.13440","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Objective</h3>\n \n <p>To describe a case of a suspected anaphylactoid reaction to mannitol in a dog.</p>\n </section>\n \n <section>\n \n <h3> Case Summary</h3>\n \n <p>A 1-year-old, neutered female French Bulldog was anesthetized for a T12–T13 dorsal laminectomy surgery for a previously diagnosed spinal arachnoid diverticulum. Perioperatively, the spinal cord appeared grossly edematous, and IV mannitol administration was elected. Midway through administration of mannitol, peracute erythema and angioedema were noted around the patient's tongue, muzzle, and paws. The dog's tongue grew to approximately twice its normal size. All vital parameters remained within normal limits. The dog was treated intravenously with dexamethasone and intramuscularly with mepyramine maleate. The remainder of the anesthetization was uneventful. The swelling completely resolved during the 2-hour recovery period, but careful management of the enlarged tongue was required to prevent airway occlusion.</p>\n </section>\n \n <section>\n \n <h3> New or Unique Information Provided</h3>\n \n <p>This is the first reported case of a suspected anaphylactoid reaction to IV administration of mannitol in a dog.</p>\n </section>\n </div>","PeriodicalId":17603,"journal":{"name":"Journal of veterinary emergency and critical care","volume":"35 1","pages":"88-91"},"PeriodicalIF":1.1000,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A suspected anaphylactoid reaction to intravenous administration of mannitol in a dog\",\"authors\":\"Kathleen Seddon BSc, BVSc, Georgina Stewart BVSc, DACVIM, Íde Gillespie BVMS, DACVECC\",\"doi\":\"10.1111/vec.13440\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Objective</h3>\\n \\n <p>To describe a case of a suspected anaphylactoid reaction to mannitol in a dog.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Case Summary</h3>\\n \\n <p>A 1-year-old, neutered female French Bulldog was anesthetized for a T12–T13 dorsal laminectomy surgery for a previously diagnosed spinal arachnoid diverticulum. Perioperatively, the spinal cord appeared grossly edematous, and IV mannitol administration was elected. Midway through administration of mannitol, peracute erythema and angioedema were noted around the patient's tongue, muzzle, and paws. The dog's tongue grew to approximately twice its normal size. All vital parameters remained within normal limits. The dog was treated intravenously with dexamethasone and intramuscularly with mepyramine maleate. The remainder of the anesthetization was uneventful. The swelling completely resolved during the 2-hour recovery period, but careful management of the enlarged tongue was required to prevent airway occlusion.</p>\\n </section>\\n \\n <section>\\n \\n <h3> New or Unique Information Provided</h3>\\n \\n <p>This is the first reported case of a suspected anaphylactoid reaction to IV administration of mannitol in a dog.</p>\\n </section>\\n </div>\",\"PeriodicalId\":17603,\"journal\":{\"name\":\"Journal of veterinary emergency and critical care\",\"volume\":\"35 1\",\"pages\":\"88-91\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-11-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of veterinary emergency and critical care\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1111/vec.13440\",\"RegionNum\":3,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"VETERINARY SCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of veterinary emergency and critical care","FirstCategoryId":"97","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1111/vec.13440","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
A suspected anaphylactoid reaction to intravenous administration of mannitol in a dog
Objective
To describe a case of a suspected anaphylactoid reaction to mannitol in a dog.
Case Summary
A 1-year-old, neutered female French Bulldog was anesthetized for a T12–T13 dorsal laminectomy surgery for a previously diagnosed spinal arachnoid diverticulum. Perioperatively, the spinal cord appeared grossly edematous, and IV mannitol administration was elected. Midway through administration of mannitol, peracute erythema and angioedema were noted around the patient's tongue, muzzle, and paws. The dog's tongue grew to approximately twice its normal size. All vital parameters remained within normal limits. The dog was treated intravenously with dexamethasone and intramuscularly with mepyramine maleate. The remainder of the anesthetization was uneventful. The swelling completely resolved during the 2-hour recovery period, but careful management of the enlarged tongue was required to prevent airway occlusion.
New or Unique Information Provided
This is the first reported case of a suspected anaphylactoid reaction to IV administration of mannitol in a dog.
期刊介绍：
The Journal of Veterinary Emergency and Critical Care’s primary aim is to advance the international clinical standard of care for emergency/critical care patients of all species. The journal’s content is relevant to specialist and non-specialist veterinarians practicing emergency/critical care medicine. The journal achieves it aims by publishing descriptions of unique presentation or management; retrospective and prospective evaluations of prognosis, novel diagnosis, or therapy; translational basic science studies with clinical relevance; in depth reviews of pertinent topics; topical news and letters; and regular themed issues.
The journal is the official publication of the Veterinary Emergency and Critical Care Society, the American College of Veterinary Emergency and Critical Care, the European Veterinary Emergency and Critical Care Society, and the European College of Veterinary Emergency and Critical Care. It is a bimonthly publication with international impact and adheres to currently accepted ethical standards.
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