眼眶炎症是一名年轻女性全身脂肪营养不良的先兆症状

IF 1.2 4区医学 Q3 OPHTHALMOLOGY

Ophthalmic Plastic and Reconstructive Surgery Pub Date : 2024-11-19 DOI:10.1097/IOP.0000000000002823

Julie M Shabto, Amy R Shteyman, Shanlee Stevens, Allison Coombs, Michael Kazim

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引用次数: 0

摘要

我们报告了首例伴有眼眶炎症症状的全身性脂肪营养不良病例。一名患有甲状腺功能减退症的 6 岁女性患者出现肝脾肿大、淋巴结肿大和皮下脂肪进行性减少。接种流感疫苗后，她出现了眼眶炎症状。眼眶影像学检查显示，眼球后脂肪稀少，并有脂肪滞留。全身检查发现胰岛素抵抗和肝脂肪变性，与全身性脂肪营养不良一致。我们讨论了全身性脂肪营养不良的典型病史和检查结果，并回顾了病因、治疗方案和结果。

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Orbital Inflammatory Disease as a Presenting Symptom of Generalized Lipodystrophy in a Young Female.

We report the first case of generalized lipodystrophy with orbital inflammatory symptoms. A 6-year-old female with hypothyroidism who developed hepatosplenomegaly, lymphadenopathy, and progressive loss of subcutaneous fat. Following flu vaccination, she developed orbital inflammatory symptoms. Imaging of the orbits demonstrated a paucity of retrobulbar fat and fat stranding. Systemic workup revealed insulin resistance and hepatosteatosis, consistent with generalized lipodystrophy. We discuss the typical history and examination findings in generalized lipodystrophy and review the etiology, treatment options, and outcomes.

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来源期刊

Ophthalmic Plastic and Reconstructive Surgery 医学-外科

CiteScore

2.50

自引率

10.00%

发文量

322

审稿时长

3-8 weeks

期刊介绍： Ophthalmic Plastic and Reconstructive Surgery features original articles and reviews on topics such as ptosis, eyelid reconstruction, orbital diagnosis and surgery, lacrimal problems, and eyelid malposition. Update reports on diagnostic techniques, surgical equipment and instrumentation, and medical therapies are included, as well as detailed analyses of recent research findings and their clinical applications.