{"title":"用光学频域成像评估胫骨下中段狭窄球囊血管成形术后的血管反应","authors":"Haruya Yamane, Yasunori Ueda, Kuniyasu Ikeoka, Haruhiko Abe, Koichi Inoue, Yasushi Matsumura","doi":"10.1002/ccd.31291","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>We often experience worsening of stenosis by balloon angioplasty of infrapopliteal (IP) lesion compared with the initial stenosis. However, reports on this phenomenon are limited.</p><p><strong>Aims: </strong>The main purpose of this study is to evaluate vascular response after balloon angioplasty of IP artery stenosis.</p><p><strong>Methods: </strong>Thirteen patients (15 arteries) who underwent endovascular treatment (EVT) and follow-up angiography with optical frequency domain imaging (OFDI) of intermediate IP stenosis were included. Serial OFDI images at 3 time points (before and after EVT and at follow-up) were analyzed. Diameter and area of external elastic lamina, internal elastic lamina, and lumen were measured, and plaque area and plaque burden (PB) were calculated. PB before EVT was classified into mild, moderate, and severe by 0%-20%, 21%-40%, and 41%-60%, respectively.</p><p><strong>Results: </strong>Analyzed were 229 cross sections. External elastic lamina diameter did not change significantly among three time points (3.8 ± 0.5 [95% confidence interval (CI): 3.7 to 3.9] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, p = 0.06). Lumen area increased after EVT but became smaller at follow-up than before EVT (4.5 ± 1.5 [95% CI: 4.3 to 4.7] mm<sup>2</sup>, 5.3 ± 1.3 [95% CI: 5.1 to 5.5] mm<sup>2</sup>, 3.7 ± 1.2 [95% CI: 3.5 to 3.9] mm<sup>2</sup>, p < 0.001). Plaque area became smaller after EVT and larger at follow-up than before EVT (3.0 ± 1.7 [95% CI: 2.8 to 3.2] mm<sup>2</sup>, 2.4 ± 1.5 [95% CI: 2.2 to 2.6] mm<sup>2</sup>, 4.0 ± 1.6 [95% CI: 3.8 to 4.2] mm<sup>2</sup>, p < 0.001). Lumen area was significantly smaller at follow-up than before EVT in mild and moderate PB groups, but it was not different in severe PB group (mild PB group: 5.1 ± 1.5 [95% CI: 4.7 to 5.5] mm<sup>2</sup> vs. 4.0 ± 1.3 [95% CI: 3.7 to 4.3] mm<sup>2</sup>, p < 0.001, moderate PB group: 4.6 ± 1.3 [95% CI: 4.4 to 4.8] mm<sup>2</sup> vs. 3.6 ± 1.2 [95% CI: 3.4 to 3.8] mm<sup>2</sup>, p < 0.001, severe PB group: 3.0 ± 1.4 [95% CI: 2.5 to 3.5] mm<sup>2</sup> vs. 3.1 ± 1.0 [95% CI: 2.7 to 3.5] mm<sup>2</sup>, p = 0.93).</p><p><strong>Conclusions: </strong>Balloon angioplasty of intermediate IP artery stenosis with mild or moderate PB led to smaller lumen area at follow-up than before EVT.</p>","PeriodicalId":9650,"journal":{"name":"Catheterization and Cardiovascular Interventions","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Vascular Response After Balloon Angioplasty of Infrapopliteal Intermediate Stenosis Evaluated by Optical Frequency Domain Imaging.\",\"authors\":\"Haruya Yamane, Yasunori Ueda, Kuniyasu Ikeoka, Haruhiko Abe, Koichi Inoue, Yasushi Matsumura\",\"doi\":\"10.1002/ccd.31291\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>We often experience worsening of stenosis by balloon angioplasty of infrapopliteal (IP) lesion compared with the initial stenosis. However, reports on this phenomenon are limited.</p><p><strong>Aims: </strong>The main purpose of this study is to evaluate vascular response after balloon angioplasty of IP artery stenosis.</p><p><strong>Methods: </strong>Thirteen patients (15 arteries) who underwent endovascular treatment (EVT) and follow-up angiography with optical frequency domain imaging (OFDI) of intermediate IP stenosis were included. Serial OFDI images at 3 time points (before and after EVT and at follow-up) were analyzed. Diameter and area of external elastic lamina, internal elastic lamina, and lumen were measured, and plaque area and plaque burden (PB) were calculated. PB before EVT was classified into mild, moderate, and severe by 0%-20%, 21%-40%, and 41%-60%, respectively.</p><p><strong>Results: </strong>Analyzed were 229 cross sections. External elastic lamina diameter did not change significantly among three time points (3.8 ± 0.5 [95% confidence interval (CI): 3.7 to 3.9] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, p = 0.06). Lumen area increased after EVT but became smaller at follow-up than before EVT (4.5 ± 1.5 [95% CI: 4.3 to 4.7] mm<sup>2</sup>, 5.3 ± 1.3 [95% CI: 5.1 to 5.5] mm<sup>2</sup>, 3.7 ± 1.2 [95% CI: 3.5 to 3.9] mm<sup>2</sup>, p < 0.001). Plaque area became smaller after EVT and larger at follow-up than before EVT (3.0 ± 1.7 [95% CI: 2.8 to 3.2] mm<sup>2</sup>, 2.4 ± 1.5 [95% CI: 2.2 to 2.6] mm<sup>2</sup>, 4.0 ± 1.6 [95% CI: 3.8 to 4.2] mm<sup>2</sup>, p < 0.001). Lumen area was significantly smaller at follow-up than before EVT in mild and moderate PB groups, but it was not different in severe PB group (mild PB group: 5.1 ± 1.5 [95% CI: 4.7 to 5.5] mm<sup>2</sup> vs. 4.0 ± 1.3 [95% CI: 3.7 to 4.3] mm<sup>2</sup>, p < 0.001, moderate PB group: 4.6 ± 1.3 [95% CI: 4.4 to 4.8] mm<sup>2</sup> vs. 3.6 ± 1.2 [95% CI: 3.4 to 3.8] mm<sup>2</sup>, p < 0.001, severe PB group: 3.0 ± 1.4 [95% CI: 2.5 to 3.5] mm<sup>2</sup> vs. 3.1 ± 1.0 [95% CI: 2.7 to 3.5] mm<sup>2</sup>, p = 0.93).</p><p><strong>Conclusions: </strong>Balloon angioplasty of intermediate IP artery stenosis with mild or moderate PB led to smaller lumen area at follow-up than before EVT.</p>\",\"PeriodicalId\":9650,\"journal\":{\"name\":\"Catheterization and Cardiovascular Interventions\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-11-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Catheterization and Cardiovascular Interventions\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1002/ccd.31291\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Catheterization and Cardiovascular Interventions","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/ccd.31291","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
The Vascular Response After Balloon Angioplasty of Infrapopliteal Intermediate Stenosis Evaluated by Optical Frequency Domain Imaging.
Background: We often experience worsening of stenosis by balloon angioplasty of infrapopliteal (IP) lesion compared with the initial stenosis. However, reports on this phenomenon are limited.
Aims: The main purpose of this study is to evaluate vascular response after balloon angioplasty of IP artery stenosis.
Methods: Thirteen patients (15 arteries) who underwent endovascular treatment (EVT) and follow-up angiography with optical frequency domain imaging (OFDI) of intermediate IP stenosis were included. Serial OFDI images at 3 time points (before and after EVT and at follow-up) were analyzed. Diameter and area of external elastic lamina, internal elastic lamina, and lumen were measured, and plaque area and plaque burden (PB) were calculated. PB before EVT was classified into mild, moderate, and severe by 0%-20%, 21%-40%, and 41%-60%, respectively.
Results: Analyzed were 229 cross sections. External elastic lamina diameter did not change significantly among three time points (3.8 ± 0.5 [95% confidence interval (CI): 3.7 to 3.9] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, 3.9 ± 0.4 [95% CI: 3.8 to 4.0] mm, p = 0.06). Lumen area increased after EVT but became smaller at follow-up than before EVT (4.5 ± 1.5 [95% CI: 4.3 to 4.7] mm2, 5.3 ± 1.3 [95% CI: 5.1 to 5.5] mm2, 3.7 ± 1.2 [95% CI: 3.5 to 3.9] mm2, p < 0.001). Plaque area became smaller after EVT and larger at follow-up than before EVT (3.0 ± 1.7 [95% CI: 2.8 to 3.2] mm2, 2.4 ± 1.5 [95% CI: 2.2 to 2.6] mm2, 4.0 ± 1.6 [95% CI: 3.8 to 4.2] mm2, p < 0.001). Lumen area was significantly smaller at follow-up than before EVT in mild and moderate PB groups, but it was not different in severe PB group (mild PB group: 5.1 ± 1.5 [95% CI: 4.7 to 5.5] mm2 vs. 4.0 ± 1.3 [95% CI: 3.7 to 4.3] mm2, p < 0.001, moderate PB group: 4.6 ± 1.3 [95% CI: 4.4 to 4.8] mm2 vs. 3.6 ± 1.2 [95% CI: 3.4 to 3.8] mm2, p < 0.001, severe PB group: 3.0 ± 1.4 [95% CI: 2.5 to 3.5] mm2 vs. 3.1 ± 1.0 [95% CI: 2.7 to 3.5] mm2, p = 0.93).
Conclusions: Balloon angioplasty of intermediate IP artery stenosis with mild or moderate PB led to smaller lumen area at follow-up than before EVT.
期刊介绍：
Catheterization and Cardiovascular Interventions is an international journal covering the broad field of cardiovascular diseases. Subject material includes basic and clinical information that is derived from or related to invasive and interventional coronary or peripheral vascular techniques. The journal focuses on material that will be of immediate practical value to physicians providing patient care in the clinical laboratory setting. To accomplish this, the journal publishes Preliminary Reports and Work In Progress articles that complement the traditional Original Studies, Case Reports, and Comprehensive Reviews. Perspective and insight concerning controversial subjects and evolving technologies are provided regularly through Editorial Commentaries furnished by members of the Editorial Board and other experts. Articles are subject to double-blind peer review and complete editorial evaluation prior to any decision regarding acceptability.
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