重新浮现的传感器 NLR 赋予非 MAX 效应器新的识别特异性。

IF 9.3 1区生物学 Q1 BIOCHEMISTRY & MOLECULAR BIOLOGY

Journal of Integrative Plant Biology Pub Date : 2024-11-19 DOI:10.1111/jipb.13805

Tongtong Zhu, Xuefeng Wu, Guixin Yuan, Dongli Wang, Vijai Bhadauria, You-Liang Peng, Junfeng Liu, Xin Zhang

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A resurfaced sensor NLR confers new recognition specificity to non-MAX effectors

Replacing the HMA domain of the rice (Oryza sativa) immune receptor RGA5 with that of the rice HMA DOMAIN-CONTAINING PROTEIN 120 (HMA120) creates a designer RGA5^HMA120 that confers resistance to Magnaporthe oryzae isolates expressing the non-MAX effector gene AVR-Pita, thus enabling the generation of new synthetic resistance genes.

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来源期刊

Journal of Integrative Plant Biology 生物-生化与分子生物学

CiteScore

18.00

自引率

5.30%

发文量

220

审稿时长

3 months

期刊介绍： Journal of Integrative Plant Biology is a leading academic journal reporting on the latest discoveries in plant biology.Enjoy the latest news and developments in the field, understand new and improved methods and research tools, and explore basic biological questions through reproducible experimental design, using genetic, biochemical, cell and molecular biological methods, and statistical analyses.