肠螺旋体病与大肠癌并存：线圈会致癌吗？

IF 0.6 Q4 GASTROENTEROLOGY & HEPATOLOGY

ACG Case Reports Journal Pub Date : 2024-11-16 eCollection Date: 2024-11-01 DOI:10.14309/crj.0000000000001557

Hannah Zuercher, Arvin Daneshmand, Eugene Stolow, Matthew Giansiracusa, Robert Allan, Antonios Sapounas

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引用次数: 0

摘要

肠螺旋体病（IS）是一种由布拉奇螺旋体细菌引起的传染性胃肠道疾病。我们详细介绍了一例极为罕见的肠螺虫病并发浸润性结直肠腺癌（CRC）的病例，患者是一名 58 岁的男性，因腹部不适和发烧而就诊。结肠镜检查发现盲肠粘膜外观异常，呈结节状，并有一个 35 毫米的直肠乙状结肠肿块。组织病理学证实了 IS 感染和 CRC。我们的病例报告首次详细介绍了 IS 与结直肠癌同时确诊的情况。它强调了对腹部不适和内镜下发现不规则结节粘膜的患者高度怀疑 IS 的必要性，尤其是在怀疑患有 CRC 的情况下。报告进一步详细阐述了 IS 与结直肠恶性肿瘤之间潜在的病理生理学联系。

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Coexistence of Intestinal Spirochetosis and Colorectal Cancer: Could the Coil be Carcinogenic?

Intestinal spirochetosis (IS) is an infectious gastrointestinal disease caused by Brachyspira bacteria. We detail an exceedingly rare case of IS with concomitant invasive colorectal adenocarcinoma (CRC) in a 58-year-old man presenting with abdominal discomfort and fever. Colonoscopic evaluation revealed abnormal-appearing, nodular cecal mucosa and a 35 mm rectosigmoid mass. Histopathology confirmed IS infection and CRC. Our case report is the first to detail IS diagnosed concurrently with colorectal cancer. It highlights the necessity of a high index of suspicion for IS in patients presenting with abdominal discomfort and endoscopic evidence of irregular nodular mucosa, particularly in the setting of suspected CRC. It further details potential pathophysiologic links between IS and colorectal malignancy.

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来源期刊

ACG Case Reports Journal GASTROENTEROLOGY & HEPATOLOGY-

自引率

14.30%

发文量

170

审稿时长

12 weeks

期刊介绍： ACG Case Reports Journal is a peer-reviewed, open-access publication that provides GI and hepatology fellows, private practice clinicians, and other healthcare providers an opportunity to share interesting case reports with their peers and with leaders in the field. ACG Case Reports Journal publishes case reports, images, videos and letters to the editor in all topics of gastroenterology and hepatology, including: Biliary Colon Endoscopy Esophagus Functional Bowel Disorders Inflammatory Bowel Disease Liver Nutrition and Obesity Pancreas Pathology Pediatric Small Bowel Stomach.