使用 MammoWave 设备优化乳腺癌检测的人工智能分层方法

IF 4.9 2区 医学 Q1 ENGINEERING, BIOMEDICAL
Mehran Taghipour-Gorjikolaie , Navid Ghavami , Lorenzo Papini , Mario Badia , Arianna Fracassini , Alessandra Bigotti , Gianmarco Palomba , Daniel Álvarez Sánchez-Bayuela , Cristina Romero Castellano , Riccardo Loretoni , Massimo Calabrese , Alberto Stefano Tagliafico , Mohammad Ghavami , Gianluigi Tiberi
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引用次数: 0

摘要

乳腺癌是全球关注的健康问题,是导致妇女死亡的第二大原因。目前的筛查方法,如乳房 X 射线照相术,由于辐射问题和检查频率的限制,面临着诸多限制,尤其是对 50 岁以下的妇女而言。利用微波信号(1 至 9 千兆赫)的 MammoWave 是一种创新、安全的乳腺癌检测技术。本文重点关注从 MammoWave 提取的数字数据,提出了一种分层方法,以应对来自两家欧洲医院的 1000 多个样本组成的多样化数据集所带来的挑战。所提出的方法包括无监督聚类,将数据分为两大类,然后在每一类中进行二元分类,以区分健康和非健康病例。在每个步骤中都仔细考虑了特征提取方法和分类器。通过观察 1 至 9 GHz 范围内子频段对诊断模型的独特影响,从而选择合适的子频段、特征提取方法和分类模型。采用优化算法和确定的成本函数来实现高且均衡的灵敏度、特异性和准确度值。实验结果表明,该技术的总体平衡性能达到了约 70%,是利用微波成像检测乳腺癌的一个重要里程碑。MammoWave 以其新颖的方法提供了一种解决方案,克服了与现有筛查方法相关的年龄和检查频率限制,有助于为更广泛的人群加强乳腺健康监测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AI-based hierarchical approach for optimizing breast cancer detection using MammoWave device
Breast cancer is a global health concern, ranking as the second leading cause of death among women. Current screening methods, such as mammography, face limitations, particularly for women under 50 due to radiation concerns and frequency of examination restrictions. MammoWave, utilizing microwave signals (1 to 9 GHz), emerges as an innovative and safe technology for breast cancer detection. This paper focuses on the numerical data extracted from MammoWave, presenting a hierarchical approach to address challenges posed by a diverse dataset of over 1000 samples from two European hospitals. The proposed approach involves unsupervised clustering to classify data into two main groups, followed by binary classification within each group to distinguish healthy and non-healthy cases. Careful consideration is given to feature extraction methods and classifiers at each step. The unique influence of sub-bands within the 1 to 9 GHz range on the diagnosis model is observed, leading to the selection of suitable sub-bands, feature extraction methods, and classification models. An optimization algorithm and a defined cost function are employed to achieve high and balanced sensitivity, specificity, and accuracy values. Experimental results showcase a promising overall balanced performance of around 70 %, representing a significant milestone in breast cancer detection using microwave imaging. MammoWave, with its novel approach, provides a solution that overcomes age and frequency of examination related limitations associated with existing screening methods, contributing to enhanced breast health monitoring for a broader population.
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来源期刊
Biomedical Signal Processing and Control
Biomedical Signal Processing and Control 工程技术-工程:生物医学
CiteScore
9.80
自引率
13.70%
发文量
822
审稿时长
4 months
期刊介绍: Biomedical Signal Processing and Control aims to provide a cross-disciplinary international forum for the interchange of information on research in the measurement and analysis of signals and images in clinical medicine and the biological sciences. Emphasis is placed on contributions dealing with the practical, applications-led research on the use of methods and devices in clinical diagnosis, patient monitoring and management. Biomedical Signal Processing and Control reflects the main areas in which these methods are being used and developed at the interface of both engineering and clinical science. The scope of the journal is defined to include relevant review papers, technical notes, short communications and letters. Tutorial papers and special issues will also be published.
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