Synthesis, characterization, insecticidal activity and antibacterial evaluation of some heterocyclic compounds containing 1,2,3-triazoles moiety

A series of 1,2,3-triazole compounds having thymol or paracetamol moieties have been designed via employing ‘click’ chemistry with copper-catalyzed azide-alkyne cycloaddition reactions. Additionally, the insecticidal characterizations of many designed products were perceived with respect to second & fourth of Spodoptera littoralis instar larvae. Numerous insecticides are revealed as novelties. As a result, numerous triazole derivatives were designed chemically to assist as analogues a comprehensive class of insecticides. With LC₅₀ value of 0.321 mg/L for second larvae instar and LC₅₀ = 0.627 mg/L four instar larvae, components 10 display the highest insecticidal bioactivity. This article deliberates how to find novel compounds that could be employed as insecticidal components in the future. A few biological and biochemical properties of the compounds produced in a laboratory environment were also examined. This work also addresses the process of finding new compounds that could be used as insecticidal products in the future. Ultimately, the antibacterial effectiveness of each developed component contrary to both Gram-positive & Gram-negative bacteria was observed.