慢性肾脏病中的动脉粥样硬化疾病。

IF 3 2区 医学 Q2 PERIPHERAL VASCULAR DISEASE
Toshiaki Nakano
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引用次数: 0

摘要

慢性肾脏病(CKD)患者是缺血性心脏病、脑血管疾病和外周动脉疾病等动脉粥样硬化性疾病的高发人群。为预防慢性肾脏病患者发生动脉粥样硬化性心血管疾病,应确定动脉硬化的病理。血管钙化是慢性肾脏病患者动脉硬化的一个特征。最近有研究报告称,冠状动脉钙化与急性冠状动脉综合征有关。慢性肾功能衰竭常常与心力衰竭有关。此外,最近的证据表明,冠状动脉钙化会影响无症状的心肌缺血。高磷血症和钙蛋白颗粒可能与血管钙化的病理过程有关。控制血管钙化的进展和典型的动脉粥样硬化危险因素对于预防慢性肾脏病患者发生动脉粥样硬化性疾病非常重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Atherosclerotic Diseases in Chronic Kidney Disease.

Patients with chronic kidney disease (CKD) have a high incidence of atherosclerotic diseases, such as ischemic heart disease, cerebrovascular disease, and peripheral arterial disease. To prevent the incidence of atherosclerotic cardiovascular disease in patients with CKD, the pathology of arteriosclerosis should be determined. Vascular calcification is a characteristic of arteriosclerosis in patients with CKD. Recent studies have reported that coronary artery calcification is associated with acute coronary syndromes. CKD is frequently associated with heart failure. Furthermore, recent evidence suggests that coronary artery calcification affects asymptomatic myocardial ischemia. Hyperphosphatemia and calciprotein particles may be involved in the pathology of vascular calcification. Controlling the progression of vascular calcification and classical atherosclerotic risk factors is important to prevent the occurrence of atherosclerotic diseases in CKD.

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来源期刊
CiteScore
6.60
自引率
15.90%
发文量
271
审稿时长
1 months
期刊介绍: JAT publishes articles focused on all aspects of research on atherosclerosis, vascular biology, thrombosis, lipid and metabolism.
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