大鼠急性乙醇中毒时磷脂的变化。

Physiologie (Bucarest) Pub Date : 1988-01-01
I Boerescu, N Gheorghe, I Boroş, L Ciuntu
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引用次数: 0

摘要

用32P研究了急性乙醇中毒对大鼠各脏器的影响。由于32P在所有细胞膜形成化合物中的结合忠实地说明了它们的结构和功能完整性,因此在急性实验中研究了来自不同器官的32P标记磷脂的水平。对雄性大鼠进行了研究,分别给药3.5和5.8 g/kg体重,并在2、4、6、24、48和72小时杀死它们。肝、脑、肾和脾的反应取决于给药剂量,并随时间变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phospholipid variation in acute ethanol intoxication in rats.

The effects of acute ethanol intoxication in different rat organs were studied with 32P. Since 32P incorporation in all compounds of cell membrane formation faithfully illustrate their structural and functional integrity, levels of 32P labelled phospholipids, from different organs were investigated in acute experiments. Researches were carried out on male rats, by administering doses of 3.5 and 5.8 g/kg body wt., and killing them at 2, 4, 6, 24, 48, and 72 hours. The response of the liver, brain, kidneys and spleen depends on the administered dose and varies with time.

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