癌症相关血栓风险预测的机器学习模型:系统回顾与元分析》。

IF 5.5 2区 医学 Q1 HEMATOLOGY
Keya Chen, Ying Zhang, Lufang Zhang, Wei Zhang, Yu Chen
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引用次数: 0

摘要

背景:虽然预测癌症相关性血栓风险的模型数量不断增加,但目前仍缺乏对机器学习预测模型的全面评估:目的:对使用机器学习预测癌症相关血栓形成的研究进行严格评估和量化:我们在 PubMed、Embase、The Cochrane Library、Cumulative Index to Nursing and Allied Health Literature 等相关数据库中检索了相关出版物(从开始到 2023 年 12 月 1 日)。采用预测模型偏倚风险评估工具核对表来评估偏倚风险和适用性。建议分级评估、发展和评价系统用于评价系统综述的证据质量。使用 R(4.3.2 版)进行元分析:结果:共纳入 32 项研究。大部分纳入文献的偏倚风险较高,预测模型的适用性被认为是可以接受的。荟萃分析中纳入的 21 项研究表明,机器学习模型对癌症相关血栓的预测能力很强:结论:本研究纳入的大多数预测模型显示出良好的适用性和出色的预测性能,但存在较高的偏倚风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Machine learning models for risk prediction of cancer-associated thrombosis: a systematic review and meta-analysis.

Background: Although the number of models for predicting the risk of cancer-associated thrombosis has been rising, there is still a lack of comprehensive assessment for machine learning prediction models.

Objectives: This study aimed to critically appraise and quantify the performance studies using machine learning to predict cancer-associated thrombosis.

Methods: We conducted searches on PubMed, Embase, The Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, and other related databases for the related publications (from inception to December 1, 2023). The Prediction Model Risk of Bias Assessment Tool checklist was employed to evaluate the risk of bias and applicability. The Grading of Recommendations Assessment, Development and Evaluation system was used to evaluate the quality of evidence in systematic reviews. Meta-analyses were conducted using R (version 4.3.2).

Results: A total of 32 studies were included. Mostly included literature exhibited a high risk of bias, and the applicability of the prediction models was deemed acceptable. The 21 included studies in the meta-analysis demonstrated the high predictive capacity of the machine learning models for cancer-associated thrombosis.

Conclusion: Most of the prediction models included in the study showed good applicability and excellent prediction performance, but there was a high risk of bias.

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来源期刊
Journal of Thrombosis and Haemostasis
Journal of Thrombosis and Haemostasis 医学-外周血管病
CiteScore
24.30
自引率
3.80%
发文量
321
审稿时长
1 months
期刊介绍: The Journal of Thrombosis and Haemostasis (JTH) serves as the official journal of the International Society on Thrombosis and Haemostasis. It is dedicated to advancing science related to thrombosis, bleeding disorders, and vascular biology through the dissemination and exchange of information and ideas within the global research community. Types of Publications: The journal publishes a variety of content, including: Original research reports State-of-the-art reviews Brief reports Case reports Invited commentaries on publications in the Journal Forum articles Correspondence Announcements Scope of Contributions: Editors invite contributions from both fundamental and clinical domains. These include: Basic manuscripts on blood coagulation and fibrinolysis Studies on proteins and reactions related to thrombosis and haemostasis Research on blood platelets and their interactions with other biological systems, such as the vessel wall, blood cells, and invading organisms Clinical manuscripts covering various topics including venous thrombosis, arterial disease, hemophilia, bleeding disorders, and platelet diseases Clinical manuscripts may encompass etiology, diagnostics, prognosis, prevention, and treatment strategies.
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