FMRP 获得线粒体裂变控制权

IF 17.3 1区生物学 Q1 CELL BIOLOGY

Nature Cell Biology Pub Date : 2024-11-15 DOI:10.1038/s41556-024-01567-9

Carissa L. Sirois, Soraya O. Sandoval, Xinyu Zhao

引用次数: 0

摘要

线粒体的分裂和融合对神经元至关重要。RNA 结合蛋白 FMRP 可调节线粒体的动力学，包括神经元中的融合和贩运。现在，一项研究确定了FMRP调节线粒体裂变的机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

FMRP gains mitochondrial fission control

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FMRP gains mitochondrial fission control

Mitochondrial fission and fusion are crucial for neurons. The RNA-binding protein FMRP regulates mitochondrial dynamics, including fusion and trafficking in neurons. A study now identifies a mechanism by which FMRP regulates mitochondrial fission.

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来源期刊

Nature Cell Biology 生物-细胞生物学

CiteScore

28.40

自引率

0.90%

发文量

219

审稿时长

3 months

期刊介绍： Nature Cell Biology, a prestigious journal, upholds a commitment to publishing papers of the highest quality across all areas of cell biology, with a particular focus on elucidating mechanisms underlying fundamental cell biological processes. The journal's broad scope encompasses various areas of interest, including but not limited to: -Autophagy -Cancer biology -Cell adhesion and migration -Cell cycle and growth -Cell death -Chromatin and epigenetics -Cytoskeletal dynamics -Developmental biology -DNA replication and repair -Mechanisms of human disease -Mechanobiology -Membrane traffic and dynamics -Metabolism -Nuclear organization and dynamics -Organelle biology -Proteolysis and quality control -RNA biology -Signal transduction -Stem cell biology