COVID-19 患者术后小肠多发性穿孔--病例报告。

IF 1.2 4区 医学 Q4 DEVELOPMENTAL BIOLOGY
Theodor Viorel Dumitrescu, Cristian Meşină, Mihai Călin Ciorbagiu, Luana Corina Lascu, Sorina Octavia Honţaru, Nina Ionovici, Laurenţiu Mogoantă, Stelian Ştefăniţă Mogoantă
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引用次数: 0

摘要

在 2019 年冠状病毒病(COVID-19)大流行期间,感染严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)的症状多种多样,除了呼吸道症状外,还有其他临床症状,如血栓形成、术后出血、急性肝肾功能衰竭、消化功能紊乱(呕吐和腹泻便)等。我们介绍了一例被确诊为横结肠肿瘤和无症状 SARS-CoV-2 感染的患者,该患者来到罗马尼亚克拉约瓦县临床医院急诊室(ER)就诊,临床表现为低位肠梗阻。医院决定对其进行手术治疗,并将右半结肠切除术延伸至左半结肠,同时进行了末端回肠造口术。术后情况良好,肠道恢复通畅,术后第三天出院。术后第五天,患者因弥漫性腹痛、无肠道转运和胀气返回急诊科。临床腹部检查发现,触诊时有腹胀音。由于怀疑是术后闭塞,再次进行了急诊开腹手术,发现小肠有五个穿孔,并伴有粪样腹膜炎和机化性炎症闭塞。这些穿孔没有任何明显的病变基底,其中四个位于空肠,一个位于回肠末端。组织病理学检查显示,肠壁上有出血和新近形成的跨壁血栓,很可能是由 COVID-19 引起的。在没有任何呼吸道症状的情况下,COVID-19 感染引起了多处肠道病变,导致腹膜炎和脓毒性休克,随后患者死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postoperative multiple perforations of the small bowel in a patient with COVID-19 - case report.

During the coronavirus disease 2019 (COVID-19) pandemic, the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presented quite a diverse symptomatology, in addition to respiratory symptoms, while other clinical signs such as thrombosis, postoperative hemorrhages, acute kidney or liver failure, digestive disorders (vomiting and diarrheal stools) were also reported. We present the case of a patient diagnosed with transverse colon neoplasm and asymptomatic SARS-CoV-2 infection, who presented to the Emergency Room (ER) of the Emergency County Clinical Hospital, Craiova, Romania, with a clinical picture of low intestinal occlusion. Surgery was decided and a right hemicolectomy extended to the left, with terminal ileostomy performed. The postoperative evolution was favorable, with the resumption of intestinal transit and discharge on the third postoperative day. The patient returned to the ER Department on the fifth day after surgery, with diffuse abdominal pain, absence of intestinal transit and flatulence. Clinical examination of the abdomen revealed the presence of bloating sounds on palpation. Emergency laparotomy was again performed with the suspicion of postoperative occlusion and five perforations were found in the small bowel, associated with fecaloid peritonitis and mechanic-inflammatory occlusion. The perforations were without any obvious lesion substrate, four of them being located on the jejunum and one on the terminal ileum. The histopathological examination revealed hemorrhage and recent transmural thrombosis on the intestinal wall, most likely caused by COVID-19. Without any respiratory symptoms, the COVID-19 infection caused multiple intestinal lesions, leading to peritonitis and septic shock, followed by the patient's death.

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来源期刊
CiteScore
1.70
自引率
20.00%
发文量
221
审稿时长
3-8 weeks
期刊介绍: Romanian Journal of Morphology and Embryology (Rom J Morphol Embryol) publishes studies on all aspects of normal morphology and human comparative and experimental pathology. The Journal accepts only researches that utilize modern investigation methods (studies of anatomy, pathology, cytopathology, immunohistochemistry, histochemistry, immunology, morphometry, molecular and cellular biology, electronic microscopy, etc.).
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