通过改变生活方式逆转骨质密度流失:病例报告

IF 1.5 Q3 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Judith A Potashkin, Namhee Kim
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引用次数: 0

摘要

美国约有 1000 万人患有骨质疏松症,4400 万人的骨质密度较低,这使他们面临骨折的风险。这给我们的医疗保健系统带来了巨大的负担,因为大约四分之一的髋部骨折患者再也无法恢复全部功能,需要护理,而对于 50 岁以上的患者,24% 的患者会在一年内死亡。口服双膦酸盐通常被用作治疗骨质疏松症的一线疗法,但患者经常会出现明显的副作用。此外,双膦酸盐还能抑制骨质流失,因为它能使清除旧骨的破骨细胞凋亡,从而使旧骨堆积,并减缓生成新骨的成骨细胞的活动,从而影响骨质。作为一种替代方法,对骨骼有益的生活方式,包括摄入钙和维生素 D、运动、戒烟和减少酒精摄入量,可以减少骨质流失。本病例报告描述了一位绝经后妇女改变生活方式,包括饮食和运动,在两年内增加了骨矿物质密度,而且没有任何负面影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Reversal of Bone Mineral Density Loss Through Lifestyle Changes: A Case Report.

Approximately 10 million individuals in the United States have osteoporosis and 44 million have low bone mineral density which puts them at risk for bone breaks. This presents a large burden on our health care system since about one-quarter of hip fracture patients never regain full function, need nursing care, and, for those over age 50, 24% die within one year. Oral bisphosphonates are often used as first-line therapy for the treatment of osteoporosis; however, patients frequently experience significant side effects. In addition, bisphosphonates inhibit bone loss by initiating apoptosis in osteoclasts that remove old bone, thus allowing old bone to accumulate and slowing the activity of osteoblasts that create new bone, thereby affecting bone quality. As an alternative, a bone-friendly lifestyle, including calcium and vitamin D consumption, exercise, smoking cessation, and a decrease in alcohol intake, may reduce bone loss. This case report describes lifestyle changes that included diet and exercise that increased bone mineral density in two years in a post-menopausal woman with no negative side effects.

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来源期刊
American Journal of Lifestyle Medicine
American Journal of Lifestyle Medicine PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.10
自引率
15.80%
发文量
119
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