番茄红素与代谢性疾病的关系。

IF 4.8 2区 医学 Q1 NUTRITION & DIETETICS
Nutrients Pub Date : 2024-10-30 DOI:10.3390/nu16213708
Anna Kulawik, Judyta Cielecka-Piontek, Bogusław Czerny, Adam Kamiński, Przemysław Zalewski
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引用次数: 0

摘要

背景:代谢综合征、肥胖和 2 型糖尿病密切相关:代谢综合征、肥胖和 2 型糖尿病密切相关。它们的特点是慢性炎症和氧化应激。肥胖是代谢综合征和 2 型糖尿病最重要的风险因素。代谢综合征的特点是胰岛素抵抗和血糖水平升高等。这些疾病会导致 2 型糖尿病的发生,而 2 型糖尿病又会加剧其他代谢问题。方法大量研究表明,饮食和营养物质对预防和治疗这些疾病有重大影响。番茄红素就是其中一种。番茄红素是一种天然类胡萝卜素,具有独特的化学结构。由于其共轭双键和中和活性氧的能力,它具有很强的抗氧化和消炎特性。番茄红素的这些特性间接影响了许多细胞过程。文章介绍了在动物模型和人体中对这种类胡萝卜素在代谢问题中的活性进行的研究。结果:研究结果表明,番茄红素的抗氧化和抗炎活性使其有望成为预防和治疗代谢综合征、肥胖症和 2 型糖尿病的候选物质。结论:本综述强调了番茄红素作为一种有益的膳食补充剂在改善代谢健康和降低相关慢性疾病风险方面的潜力。所述病症属于人群疾病,因此对番茄红素等化合物特性的研究越来越受欢迎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Relationship Between Lycopene and Metabolic Diseases.

Background: Metabolic syndrome, obesity, and type 2 diabetes are closely related. They are characterized by chronic inflammation and oxidative stress. Obesity is the most important risk factor for metabolic syndrome and type 2 diabetes. Metabolic syndrome is characterized by insulin resistance and elevated blood glucose levels, among other conditions. These disorders contribute to the development of type 2 diabetes, which can exacerbate other metabolic problems. Methods: Numerous studies indicate that diet and nutrients can have a major impact on preventing and treating these conditions. One such ingredient is lycopene. It is a naturally occurring carotenoid with a unique chemical structure. It exhibits strong antioxidant and anti-inflammatory properties due to its conjugated double bonds and its ability to neutralize reactive oxygen species. Its properties make lycopene indirectly affect many cellular processes. The article presents studies in animal models and humans on the activity of this carotenoid in metabolic problems. Results: The findings suggest that lycopene's antioxidant and anti-inflammatory activities make it a promising candidate for the prevention and treatment of metabolic syndrome, obesity, and type 2 diabetes. Conclusions: This review underscores the potential of lycopene as a beneficial dietary supplement in improving metabolic health and reducing the risk of associated chronic diseases. The conditions described are population diseases, so research into compounds with properties such as lycopene is growing in popularity.

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来源期刊
Nutrients
Nutrients NUTRITION & DIETETICS-
CiteScore
9.20
自引率
15.30%
发文量
4599
审稿时长
16.74 days
期刊介绍: Nutrients (ISSN 2072-6643) is an international, peer-reviewed open access advanced forum for studies related to Human Nutrition. It publishes reviews, regular research papers and short communications. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced.
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