生长激素释放因子和前列腺素E2在灌注大鼠垂体前细胞系统中对生长激素释放的控制。

Reproduction, nutrition, developpement Pub Date : 1988-01-01

V Fafeur, C Tiberghien, F Haour, F Dray

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引用次数: 0

摘要

使用过量的大鼠垂体细胞，我们发现生长激素释放因子(GRF)和前列腺素E2 (PGE2)在动力学和反应幅度方面以相似的方式增加生长激素(GH)的分泌。此外，我们的数据表明，它们主要通过camp依赖机制刺激GH分泌。

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[Control of growth hormone release by growth hormone-releasing factor and prostaglandin E2 in a system of perfused rat anterior pituitary cells].

Using superfused rat pituitary cells we showed that the growth hormone-releasing factor (GRF) and prostaglandin E2 (PGE2) increased growth hormone (GH) secretion in a similar manner in terms of kinetics and amplitude of responses. Moreover, our data suggest that they stimulate GH secretion mainly by cAMP-dependent mechanisms.

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Reproduction, nutrition, developpement

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