Alice Monzani, Giulia Genoni, Amanda Papa, Noemi Paggi, Eleonora Capra, Francesca Brustia, Ivana Rabbone
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引用次数: 0
摘要
导言：神经系统表现可能是乳糜泻（CD）的先兆。小儿发作性阵发性非癫痫事件（PNEEs）并不包括在其中：我们报告了两名儿童的病例，他们在出现眼部 PNEEs 的同时伴有可诱发 CD 的轻微症状，随后被诊断为 CD，并在无麸质饮食后 PNEEs 消失。我们回顾了2019-2023年因眼部PNEE接受神经学评估的12名患者的数据：3人（25%）随后被诊断为CD：结论：眼部 PNEE 可能是 CD 的一种表现形式。在 PNEE 的诊断工作中，可纳入 CD 筛查，以避免不必要的检查，并及时开始无麸质饮食，这可能会带来良好的临床反应。
Case Report: Ocular paroxysmal non-epileptic events as the presenting sign of celiac disease in children: a case series.
Introduction: Neurologic manifestations may be presenting signs of celiac disease (CD). Pediatric-onset paroxysmal non-epileptic events (PNEEs) are not included among them.
Cases presentation: We report the case of two children who presented with ocular PNEEs in association with mild symptoms evocative for CD, who were subsequently diagnosed with CD and experienced regression of PNEEs on a gluten-free diet. Data from 12 patients undergoing neurological evaluation in 2019-2023 for ocular PNEEs were reviewed: 3 (25%) had a subsequent diagnosis of CD.
Conclusions: Ocular PNEEs could be a presenting manifestation of CD. In the diagnostic work-up of PNEEs, screening for CD could be included, both to avoid unnecessary tests and to promptly start a gluten-free diet, which might lead to a favorable clinical response.
期刊介绍：
Frontiers in Pediatrics (Impact Factor 2.33) publishes rigorously peer-reviewed research broadly across the field, from basic to clinical research that meets ongoing challenges in pediatric patient care and child health. Field Chief Editors Arjan Te Pas at Leiden University and Michael L. Moritz at the Children''s Hospital of Pittsburgh are supported by an outstanding Editorial Board of international experts. This multidisciplinary open-access journal is at the forefront of disseminating and communicating scientific knowledge and impactful discoveries to researchers, academics, clinicians and the public worldwide.
Frontiers in Pediatrics also features Research Topics, Frontiers special theme-focused issues managed by Guest Associate Editors, addressing important areas in pediatrics. In this fashion, Frontiers serves as an outlet to publish the broadest aspects of pediatrics in both basic and clinical research, including high-quality reviews, case reports, editorials and commentaries related to all aspects of pediatrics.
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