腹腔镜袖状胃切除术后胃食管反流的手术治疗策略。

IF 3.9 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Frontiers in Endocrinology Pub Date : 2024-10-29 eCollection Date: 2024-01-01 DOI:10.3389/fendo.2024.1463567
Genzheng Liu, Pengpeng Wang, Shuman Ran, Xiaobin Xue, Hua Meng
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引用次数: 0

摘要

减肥手术已成为对抗肥胖症的有效治疗方法。作为最常见的减肥手术,腹腔镜袖带胃切除术(LSG)具有长期有效的减重效果。然而,有研究报告称,LSG术后患者胃食管反流病(GERD)的发病率有所增加。对于那些对常规口服抑酸药物无效的患者,手术干预成为了考虑因素。袖带胃切除术后最常进行的翻修手术是 Roux-en-Y 胃旁路术,它可以有效缓解患者的反流症状,对于效果不理想或体重反弹的患者,还能继续促进体重减轻。除这一成熟的手术外,腹腔镜磁性括约肌增强术(MSA)等创新技术也在探索之中。磁性括约肌增强术创伤小,反流治疗效果好,其安全性和有效性也得到了文献的支持,是未来治疗胃食管反流的一种很有前景的工具。本文还探讨了内镜干预在袖状胃切除术后患者胃食管反流治疗中的作用。虽然这些方法已显示出一定的治疗效果,但由于缺乏更多临床数据的支持,其疗效仍需进一步研究。对于术前有食管裂孔疝或胃食管反流症状的患者,目前一些专家考虑将 LSG 与食管裂孔疝修补术或胃底折叠术结合使用,以减轻或预防术后反流症状。这两种手术方法都取得了良好的效果;但是,加用胃底折叠术还需要进一步研究其长期效果和潜在的术后并发症。本文收集并研究了目前针对 LSG 术后难治性胃食管反流的腹腔镜和内镜治疗方法,以及术前患有胃食管反流或食管裂孔疝的患者同时接受 LSG 治疗的情况。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical treatment strategies for gastroesophageal reflux after laparoscopic sleeve gastrectomy.

Bariatric surgery has emerged as an effective therapeutic approach for combating obesity. As the most commonly performed bariatric surgery, laparoscopic sleeve gastrectomy (LSG) has a long-term and effective outcome in weight reduction. However, studies have reported an increased incidence of gastroesophageal reflux disease (GERD) among patients after LSG. For those who fail to respond to conventional oral acid-suppressing medication, surgical intervention comes into consideration. The most commonly performed revisional surgery for sleeve gastrectomy is the Roux-en-Y gastric bypass, which can effectively alleviate the symptoms of reflux in patients and also continues to promote weight loss in patients who have not achieved satisfactory results or have experienced weight regain. In addition to this established procedure, innovative techniques such as laparoscopic magnetic sphincter augmentation (MSA) are being explored. MSA is less invasive, has good reflux treatment outcomes, and its safety and efficacy are supported by the literature, making it a promising tool for the future treatment of gastroesophageal reflux. This article also explores the role of endoscopic interventions for GERD treatment of post-sleeve gastrectomy patients. Although these methods have shown some therapeutic effect, their efficacy still requires further study due to a lack of support from more clinical data. For patients with preoperative hiatal hernia or gastroesophageal reflux symptoms, some experts now consider performing LSG combined with hiatal hernia repair or fundoplication to alleviate or prevent postoperative reflux symptoms. Both of these surgical approaches have demonstrated favorable outcomes; however, the addition of fundoplication requires further investigation regarding its long-term effects and potential postoperative complications. This article gathers and examines the current laparoscopic and endoscopic treatments for refractory gastroesophageal reflux following LSG, as well as the concurrent treatment of LSG in patients with preoperative gastroesophageal reflux or hiatal hernia.

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来源期刊
Frontiers in Endocrinology
Frontiers in Endocrinology Medicine-Endocrinology, Diabetes and Metabolism
CiteScore
5.70
自引率
9.60%
发文量
3023
审稿时长
14 weeks
期刊介绍: Frontiers in Endocrinology is a field journal of the "Frontiers in" journal series. In today’s world, endocrinology is becoming increasingly important as it underlies many of the challenges societies face - from obesity and diabetes to reproduction, population control and aging. Endocrinology covers a broad field from basic molecular and cellular communication through to clinical care and some of the most crucial public health issues. The journal, thus, welcomes outstanding contributions in any domain of endocrinology. Frontiers in Endocrinology publishes articles on the most outstanding discoveries across a wide research spectrum of Endocrinology. The mission of Frontiers in Endocrinology is to bring all relevant Endocrinology areas together on a single platform.
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