在肺肝联合移植中采用 "肝脏优先 "方法可提供与传统 "肺脏优先 "方法相当的结果：一项 UNOS 研究。

IF 1.9 4区医学 Q2 SURGERY

Clinical Transplantation Pub Date : 2024-11-13 DOI:10.1111/ctr.70003

Yizhan Guo, John Ryan, Ernest Chan, Masashi Furukawa, Chadi A. Hage, Pablo G. Sanchez

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引用次数: 0

摘要

每年都会为部分患者提供多器官移植手术。器官移植的先后顺序取决于缺血时间、移植耐受性和重症器官优先策略。在肺肝移植中，肺异体移植通常先于肝脏植入。先肝后肺的策略在理论上有一些优势，一些中心已经报告了一系列病例，引发了人们对这种方法的可行性和潜在益处的兴趣。在这项对器官共享联合网络（UNOS）数据库的当代研究中，我们评估并报告了采用这两种策略的结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Utilization of the Liver-First Approach in Combined Lung-Liver Transplant Provides Comparable Outcomes to the Traditional Lung-First Approach: A UNOS Study

Multiorgan transplantation is offered to a selected group of patients every year. The sequence in which organs are transplanted depends on ischemic time graft tolerance and the sickest organ first strategy. In the case of Lung-Liver transplantation, lung allografts are usually implanted before the liver. There are some theoretical advantages to a liver-first strategy and a few centers have reported a series of cases that spark a growing interest in the feasibility and potential benefits of this approach. In this contemporary study of the United Network for Organ Sharing (UNOS) database, we evaluate and report outcomes using either strategy.

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来源期刊

Clinical Transplantation 医学-外科

CiteScore

3.70

自引率

4.80%

发文量

286

审稿时长

2 months

期刊介绍： Clinical Transplantation: The Journal of Clinical and Translational Research aims to serve as a channel of rapid communication for all those involved in the care of patients who require, or have had, organ or tissue transplants, including: kidney, intestine, liver, pancreas, islets, heart, heart valves, lung, bone marrow, cornea, skin, bone, and cartilage, viable or stored. Published monthly, Clinical Transplantation’s scope is focused on the complete spectrum of present transplant therapies, as well as also those that are experimental or may become possible in future. Topics include: Immunology and immunosuppression; Patient preparation; Social, ethical, and psychological issues; Complications, short- and long-term results; Artificial organs; Donation and preservation of organ and tissue; Translational studies; Advances in tissue typing; Updates on transplant pathology;. Clinical and translational studies are particularly welcome, as well as focused reviews. Full-length papers and short communications are invited. Clinical reviews are encouraged, as well as seminal papers in basic science which might lead to immediate clinical application. Prominence is regularly given to the results of cooperative surveys conducted by the organ and tissue transplant registries. Clinical Transplantation: The Journal of Clinical and Translational Research is essential reading for clinicians and researchers in the diverse field of transplantation: surgeons; clinical immunologists; cryobiologists; hematologists; gastroenterologists; hepatologists; pulmonologists; nephrologists; cardiologists; and endocrinologists. It will also be of interest to sociologists, psychologists, research workers, and to all health professionals whose combined efforts will improve the prognosis of transplant recipients.