靛蓝、靛红和异靛蓝的 N-糖苷：蓝色、红色和黄色糖及其抗癌活性。

IF 2.2 4区化学 Q2 CHEMISTRY, ORGANIC

Beilstein Journal of Organic Chemistry Pub Date : 2024-11-08 eCollection Date: 2024-01-01 DOI:10.3762/bjoc.20.240

Peter Langer

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引用次数: 0

摘要

几个世纪以来，靛蓝、靛蓝素和异靛蓝衍生物一直被用作颜料。自 20 世纪 90 年代以来，这类化合物化学的一个新方面是它们对各种癌症的活性。靛蓝、靛蓝素和异靛蓝的 N-糖苷（蓝色、红色和黄色糖）因其抗癌活性高和结构新颖而受到特别关注。本文介绍了这些化合物的合成和抗癌活性。

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N-Glycosides of indigo, indirubin, and isoindigo: blue, red, and yellow sugars and their cancerostatic activity.

Indigo, indirubin, and isoindigo derivatives have been used for centuries as pigments. Since the 1990s, a new aspect of the chemistry of this type of compounds is their activity against various types of cancer. N-Glycosides of indigo, indirubin, and isoindigo, blue, red, and yellow sugars, turned out to be of special interest because of their high cancerostatic activity and structural novelty. The present article provides an account on the synthesis and anticancer activity of these compounds.

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来源期刊

Beilstein Journal of Organic Chemistry 化学-有机化学

CiteScore

4.90

自引率

3.70%

发文量

167

审稿时长

1.4 months

期刊介绍： The Beilstein Journal of Organic Chemistry is an international, peer-reviewed, Open Access journal. It provides a unique platform for rapid publication without any charges (free for author and reader) – Platinum Open Access. The content is freely accessible 365 days a year to any user worldwide. Articles are available online immediately upon publication and are publicly archived in all major repositories. In addition, it provides a platform for publishing thematic issues (theme-based collections of articles) on topical issues in organic chemistry. The journal publishes high quality research and reviews in all areas of organic chemistry, including organic synthesis, organic reactions, natural product chemistry, structural investigations, supramolecular chemistry and chemical biology.