揭开非编码 RNA 在儿科呼吸系统疾病中的隐秘力量。

IF 2.5 4区医学 Q3 ALLERGY

Allergologia et immunopathologia Pub Date : 2024-11-01 eCollection Date: 2024-01-01 DOI:10.15586/aei.v52i6.1127

Shishu Yu, Lili Chen, Mingyao Zhang, Yu Lu

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引用次数: 0

摘要

儿童呼吸系统疾病是常见的健康问题，严重影响他们的生活质量和健康状况，与成人相比，儿童呼吸系统疾病有其独特的挑战。越来越多的研究集中于与各种疾病（如儿科呼吸系统疾病）的发展有关的表观遗传机制。据报道，非编码 RNA（ncRNA），尤其是长非编码 RNA、microRNA 和环状 RNA 在儿科呼吸系统疾病中发挥着调控作用，其突变或异常表达与这些疾病的发生密切相关。在这篇综述中，我们主要讨论了这三种 ncRNA 在儿科呼吸系统疾病中的功能。

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Unveiling the hidden power of noncoding RNAs in pediatric respiratory diseases.

Respiratory diseases in children are common health problems that significantly impact their quality of life and health status, and this has its own unique challenges compared to adults. A growing body of research has focused on epigenetic mechanisms that relate with the development of various diseases, such as pediatric respiratory diseases. Noncoding RNAs (ncRNAs), especially long noncoding RNAs, microRNA, and circular RNA, are reported to play a regulatory role in pediatric respiratory diseases whose mutations or aberrant expressions are strongly associated with the development of these diseases. In this review, we mainly discussed the functions of these three ncRNAs in pediatric respiratory diseases.

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来源期刊

Allergologia et immunopathologia 医学-过敏

CiteScore

3.70

自引率

0.00%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Founded in 1972 by Professor A. Oehling, Allergologia et Immunopathologia is a forum for those working in the field of pediatric asthma, allergy and immunology. Manuscripts related to clinical, epidemiological and experimental allergy and immunopathology related to childhood will be considered for publication. Allergologia et Immunopathologia is the official journal of the Spanish Society of Pediatric Allergy and Clinical Immunology (SEICAP) and also of the Latin American Society of Immunodeficiencies (LASID). It has and independent international Editorial Committee which submits received papers for peer-reviewing by international experts. The journal accepts original and review articles from all over the world, together with consensus statements from the aforementioned societies. Occasionally, the opinion of an expert on a burning topic is published in the "Point of View" section. Letters to the Editor on previously published papers are welcomed. Allergologia et Immunopathologia publishes 6 issues per year and is included in the major databases such as Pubmed, Scopus, Web of Knowledge, etc.