修正或抑制：人类特异性突触新生的机制。

IF 14.7 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2024-11-06 DOI:10.1016/j.neuron.2024.10.011

Jenelle L Wallace, Alex A Pollen

引用次数: 0

摘要

在本期《神经元与细胞报告》（Neuron and Cell Reports）上，Libé-Philippot 等人1 和 Assendorp 等人2 发现了人类特异性 SRGAP2C、突触调节因子 SRGAP2A 以及神经发育障碍相关蛋白 SYNGAP1 和 CTNND2 之间的相互作用，这些相互作用减缓了人类神经元的突触成熟。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Rev or restrain: Mechanisms of human-specific synaptic neoteny.

In the current issues of Neuron and Cell Reports, Libé-Philippot et al.¹ and Assendorp et al.² identify interactions between human-specific SRGAP2C, synaptic regulator SRGAP2A, and neurodevelopmental disorder-associated proteins SYNGAP1 and CTNND2 that slow synaptic maturation in human neurons.

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.