在肝硬化患者非选择性β-受体阻滞剂的候选药物选择方面，无创算法优于 HVPG

IF 3.7 2区生物学 Q1 BIOCHEMICAL RESEARCH METHODS

ACS Synthetic Biology Pub Date : 2024-11-13 DOI:10.1016/j.jhep.2024.11.011

Emma Vanderschueren

引用次数: 0

摘要

作者贡献构思、数据整理、正式分析和手稿撰写由 EV 和 WL 完成。财务支持无。竞争利益声明WL 担任 Cook Medical、MRM Health 和 CSL Behring 的顾问，并从波士顿科学公司获得演讲费。没有隐瞒其他利益冲突。感谢 Antonio Colecchia 教授协助提供验证队列的其他数据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Non-invasive algorithms could outperform HVPG in selecting candidates for non-selective beta-blockers in cirrhosis

Section snippets

Author contributions

Conceptualization, data curation, formal analysis and writing of the manuscript were performed by EV and WL.

Financial support

None.

Declaration of Competing Interest

WL serves as a consultant for Cook Medical, MRM Health, and CSL Behring, and has received speaker’s fees from Boston Scientific. No other conflicts of interest were withheld.

Acknowledgements

We wish to thank Prof. Antonio Colecchia for his assistance in providing additional data from the validation cohort.

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来源期刊

ACS Synthetic Biology 生物-

CiteScore

8.00

自引率

10.60%

发文量

380

审稿时长

6-12 weeks

期刊介绍： The journal is particularly interested in studies on the design and synthesis of new genetic circuits and gene products; computational methods in the design of systems; and integrative applied approaches to understanding disease and metabolism. Topics may include, but are not limited to: Design and optimization of genetic systems Genetic circuit design and their principles for their organization into programs Computational methods to aid the design of genetic systems Experimental methods to quantify genetic parts, circuits, and metabolic fluxes Genetic parts libraries: their creation, analysis, and ontological representation Protein engineering including computational design Metabolic engineering and cellular manufacturing, including biomass conversion Natural product access, engineering, and production Creative and innovative applications of cellular programming Medical applications, tissue engineering, and the programming of therapeutic cells Minimal cell design and construction Genomics and genome replacement strategies Viral engineering Automated and robotic assembly platforms for synthetic biology DNA synthesis methodologies Metagenomics and synthetic metagenomic analysis Bioinformatics applied to gene discovery, chemoinformatics, and pathway construction Gene optimization Methods for genome-scale measurements of transcription and metabolomics Systems biology and methods to integrate multiple data sources in vitro and cell-free synthetic biology and molecular programming Nucleic acid engineering.