终于回家了混合信号引导记忆 T 细胞前往居住地

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2024-11-12 DOI:10.1016/j.immuni.2024.10.008

Kalle Liimatta, Elina I. Zúñiga

引用次数: 0

摘要

组织驻留记忆 T 细胞（TRM）能适应不同的环境，提供局部长期保护。在本期《免疫》杂志上，Obers 等人和 Raynor 等人展示了饮食、共生动物和宿主因素如何决定 TRM 细胞在不同组织中的发育、维持和功能。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Home at last: Mixed signals guide memory T cells to residency

Tissue-resident memory T (T_RM) cells adapt to diverse environments, providing local long-term protection. In this issue of Immunity, Obers et al. and Raynor et al. demonstrate how diet, commensals, and host factors determine T_RM cell development, maintenance, and function across tissues.

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.