嵌毛在儿童顽固性角膜炎中的作用:临床研究。

Qi-Hao Yao, Hui-Lin Zhi, Xiu-Jiao Xia, Ze-Hu Liu
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引用次数: 0

摘要

头癣是发展中国家常见的公共卫生问题,其严重形式包括角膜炎。然而,顽固性头癣或角膜炎的基本机制和标准治疗方法仍存在争议。在这项研究中,我们调查了儿童顽固性毛囊角化症中的倒生毛发和相应的治疗方法。我们从 2020 年 1 月至 2024 年 6 月期间杭州市第三人民医院皮肤科的 312 例头癣病例中选取了患有顽固性毛囊角化症的儿童。在钙氟白染色和常规培养下,通过直接显微镜检查确定是否存在真菌感染。通过皮肤镜直接观察倒生毛发的结构,然后使用无菌工具拔除倒生毛发。在 312 例头癣患者中,共有 6 例患有顽固性角化病。在皮肤镜下确定毛发内生,并通过小手术将其拔除。除一名患者继续口服特比萘芬外,其余五例患者均通过单纯拔毛治愈。由真菌感染引起的毛发倒生可能会加重头癣的持续病程。我们的研究表明,倒生毛发可通过直接皮肤镜检查确认,患者在皮肤镜下接受拔除治疗后病情明显好转。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The role of ingrown hairs in persistent kerion of children: A clinical study.

Tinea capitis, a common public health problem in developing countries, has severe forms such as kerion. However, the underlying mechanisms and standard treatments for persistent cases of tinea capitis or kerion remain controversial. In this work, we investigate the ingrown hairs and corresponding treatment in persistent kerion of children. Children with persistent kerion were enrolled among 312 cases of tinea capitis at the Department of Dermatology, Hangzhou Third People's Hospital from January 2020 to June 2024. The presence of fungal infection was ascertained by direct microscopic examination under calcofluor white staining and routine culture. The structure of the ingrown hairs was observed directly by a dermatoscope, which was subsequently extracted using sterile tools. A total of six cases of persistent kerion among 312 cases of tinea capitis were enrolled. Ingrown hairs were ascertained under dermatoscopy and extracted by minor operation. Except for one patient who continued oral terbinafine, the other five cases were cured by removal alone. Ingrown hairs, induced by fungal infection, may be an aggravating factor of persistent course of tinea capitis. Our study demonstrated that the presence of ingrown hairs could be confirmed through direct dermatoscopy, and patients experienced significant improvement following removal treatment under dermatoscopy.

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