Francisco Polo Tirado, Asaad Nakhle, Eric Gnall, Zach Rozenbaum
{"title":"经皮穿刺抽吸缩短右侧感染性心内膜炎和植皮的血液培养物消毒时间。","authors":"Francisco Polo Tirado, Asaad Nakhle, Eric Gnall, Zach Rozenbaum","doi":"10.1007/s00392-024-02567-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Surgical intervention is associated with earlier clearance of bacteremia in infective endocarditis (IE).</p><p><strong>Aim: </strong>We hypothesized that vegetectomies using percutaneous aspiration shortens time to sterilization of blood cultures in patients with right-sided IE and vegetations.</p><p><strong>Results: </strong>The cohort included 37 patients, 23 treated conservatively, and 14 underwent percutaneous vegetectomy. The median time to blood culture sterilization among patients with bacteremia over 7 days was 16.5 (IQR 9.75-29) for patients treated conservatively and 11.5 (IQR 8.5-11.5) for those who underwent vegetectomy. The two patients who required mechanical ventilation were among the vegetectomy group, and the single patient who died during the same admission was treated conservatively. There were no complications in the vegetectomy group.</p><p><strong>Conclusion: </strong>These data are hypothesis-generating, suggesting that utilizing percutaneous aspiration in patients with right-sided IE and vegetations shortens time to sterilization of blood cultures, and possibly improves outcomes.</p>","PeriodicalId":10474,"journal":{"name":"Clinical Research in Cardiology","volume":null,"pages":null},"PeriodicalIF":3.8000,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Percutaneous aspiration for shortening time to blood cultures sterilization in right-sided infective endocarditis and vegetations.\",\"authors\":\"Francisco Polo Tirado, Asaad Nakhle, Eric Gnall, Zach Rozenbaum\",\"doi\":\"10.1007/s00392-024-02567-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Surgical intervention is associated with earlier clearance of bacteremia in infective endocarditis (IE).</p><p><strong>Aim: </strong>We hypothesized that vegetectomies using percutaneous aspiration shortens time to sterilization of blood cultures in patients with right-sided IE and vegetations.</p><p><strong>Results: </strong>The cohort included 37 patients, 23 treated conservatively, and 14 underwent percutaneous vegetectomy. The median time to blood culture sterilization among patients with bacteremia over 7 days was 16.5 (IQR 9.75-29) for patients treated conservatively and 11.5 (IQR 8.5-11.5) for those who underwent vegetectomy. The two patients who required mechanical ventilation were among the vegetectomy group, and the single patient who died during the same admission was treated conservatively. There were no complications in the vegetectomy group.</p><p><strong>Conclusion: </strong>These data are hypothesis-generating, suggesting that utilizing percutaneous aspiration in patients with right-sided IE and vegetations shortens time to sterilization of blood cultures, and possibly improves outcomes.</p>\",\"PeriodicalId\":10474,\"journal\":{\"name\":\"Clinical Research in Cardiology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2024-11-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Research in Cardiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00392-024-02567-3\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Research in Cardiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00392-024-02567-3","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
Percutaneous aspiration for shortening time to blood cultures sterilization in right-sided infective endocarditis and vegetations.
Background: Surgical intervention is associated with earlier clearance of bacteremia in infective endocarditis (IE).
Aim: We hypothesized that vegetectomies using percutaneous aspiration shortens time to sterilization of blood cultures in patients with right-sided IE and vegetations.
Results: The cohort included 37 patients, 23 treated conservatively, and 14 underwent percutaneous vegetectomy. The median time to blood culture sterilization among patients with bacteremia over 7 days was 16.5 (IQR 9.75-29) for patients treated conservatively and 11.5 (IQR 8.5-11.5) for those who underwent vegetectomy. The two patients who required mechanical ventilation were among the vegetectomy group, and the single patient who died during the same admission was treated conservatively. There were no complications in the vegetectomy group.
Conclusion: These data are hypothesis-generating, suggesting that utilizing percutaneous aspiration in patients with right-sided IE and vegetations shortens time to sterilization of blood cultures, and possibly improves outcomes.
期刊介绍：
Clinical Research in Cardiology is an international journal for clinical cardiovascular research. It provides a forum for original and review articles as well as critical perspective articles. Articles are only accepted if they meet stringent scientific standards and have undergone peer review. The journal regularly receives articles from the field of clinical cardiology, angiology, as well as heart and vascular surgery.
As the official journal of the German Cardiac Society, it gives a current and competent survey on the diagnosis and therapy of heart and vascular diseases.
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