囊性纤维化还是哮喘？用超极化氙气磁共振成像鉴别呼吸困难。

IF 2.1 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Magnetic resonance imaging Pub Date : 2024-11-02 DOI:10.1016/j.mri.2024.110271

David Wang , Cody Thornburgh , Harjeet Singh , Zach Holliday

{"title":"囊性纤维化还是哮喘？用超极化氙气磁共振成像鉴别呼吸困难。","authors":"David Wang , Cody Thornburgh , Harjeet Singh , Zach Holliday","doi":"10.1016/j.mri.2024.110271","DOIUrl":null,"url":null,"abstract":"<div><div>Hyperpolarized Xenon MRI (HPG MRI) has been studied for its potential use in assessing lung function in patients with cystic fibrosis (CF) and in patients with asthma. We present a case of a man with overlapping cystic fibrosis and allergic asthma with severe obstructive lung disease in which spirometry and computed topography (CT) imaging was unable to determine the primary cause for his uncontrolled symptoms. HPG MRI was used to guide a tissue biopsy and determine the primary driver to be allergic asthma. After starting targeted therapy for severe asthma, his symptoms have greatly improved.</div></div>","PeriodicalId":18165,"journal":{"name":"Magnetic resonance imaging","volume":"115 ","pages":"Article 110271"},"PeriodicalIF":2.1000,"publicationDate":"2024-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Cystic Fibrosis or asthma? Discerning dyspnea with hyperpolarizaed xenon gas magnetic resonance imaging\",\"authors\":\"David Wang , Cody Thornburgh , Harjeet Singh , Zach Holliday\",\"doi\":\"10.1016/j.mri.2024.110271\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Hyperpolarized Xenon MRI (HPG MRI) has been studied for its potential use in assessing lung function in patients with cystic fibrosis (CF) and in patients with asthma. We present a case of a man with overlapping cystic fibrosis and allergic asthma with severe obstructive lung disease in which spirometry and computed topography (CT) imaging was unable to determine the primary cause for his uncontrolled symptoms. HPG MRI was used to guide a tissue biopsy and determine the primary driver to be allergic asthma. After starting targeted therapy for severe asthma, his symptoms have greatly improved.</div></div>\",\"PeriodicalId\":18165,\"journal\":{\"name\":\"Magnetic resonance imaging\",\"volume\":\"115 \",\"pages\":\"Article 110271\"},\"PeriodicalIF\":2.1000,\"publicationDate\":\"2024-11-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Magnetic resonance imaging\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0730725X24002522\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Magnetic resonance imaging","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0730725X24002522","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}

引用次数: 0

摘要

超极化氙磁共振成像（HPG MRI）已被研究用于评估囊性纤维化（CF）患者和哮喘患者的肺功能。我们介绍了一例患有重叠性囊性纤维化和过敏性哮喘并伴有严重阻塞性肺部疾病的男性病例，在该病例中，肺活量测定和计算机地形图（CT）成像无法确定导致其症状失控的主要原因。HPG MRI 被用来指导组织活检，并确定主要病因是过敏性哮喘。在开始接受重症哮喘的靶向治疗后，他的症状大有好转。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Cystic Fibrosis or asthma? Discerning dyspnea with hyperpolarizaed xenon gas magnetic resonance imaging

Hyperpolarized Xenon MRI (HPG MRI) has been studied for its potential use in assessing lung function in patients with cystic fibrosis (CF) and in patients with asthma. We present a case of a man with overlapping cystic fibrosis and allergic asthma with severe obstructive lung disease in which spirometry and computed topography (CT) imaging was unable to determine the primary cause for his uncontrolled symptoms. HPG MRI was used to guide a tissue biopsy and determine the primary driver to be allergic asthma. After starting targeted therapy for severe asthma, his symptoms have greatly improved.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Magnetic resonance imaging 医学-核医学

CiteScore

4.70

自引率

4.00%

发文量

194

审稿时长

83 days

期刊介绍： Magnetic Resonance Imaging (MRI) is the first international multidisciplinary journal encompassing physical, life, and clinical science investigations as they relate to the development and use of magnetic resonance imaging. MRI is dedicated to both basic research, technological innovation and applications, providing a single forum for communication among radiologists, physicists, chemists, biochemists, biologists, engineers, internists, pathologists, physiologists, computer scientists, and mathematicians.