探索定向分离深海微生物和基因工程菌株的优势。

IF 4 3区 生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
MengYao Liu, Yali Feng, Haoran Li, Yisong Yao, Yufeng Cui, Jianwei Wang
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引用次数: 0

摘要

石油、矿物加工和环境恢复可能是危险的过程。人们常常试图利用微生物来降低风险,但陆生生物的适应性往往很弱。虽然基因工程菌株可以通过定向改造提高环境适应能力,但也存在代谢物积累、质粒稳定性差和潜在致病性等问题。从自然环境中筛选嗜极生物已成为必然选择。深海的特殊环境(高压、低温、低营养、高盐度)是嗜极端生物生长和生存的天然场所,因此从深海筛选嗜极端生物有利于产业的绿色可持续发展。本文根据极端工业所需的微生物,综述了基因工程菌株的应用现状和存在的问题。本文重点探讨了深海微生物的应用现状和优势。研究发现,其优势在于适应性强、基因稳定、环境友好、技术简单方便(与基因工程相比),具有广阔的工业过程应用前景。这篇综述拓宽了微生物的应用范围。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Exploration of the advantages of targeted isolation of deep-sea microorganisms and genetically engineered strains.

Oil, mineral processing and environmental restoration can be dangerous processes. Attempts are often made to apply microorganisms to reduce the risks, but the adaptability of terrestrial organisms is often weak. Although genetically engineered strains can improve their environmental adaptability through targeted modification, there are problems such as metabolite accumulation, poor plasmid stability and potential pathogenicity. Screening of extremophiles from the natural environment has become an inevitable choice. The special environment in the deep sea (high pressure, low temperature, low nutrition, high salinity) is a natural place for extremophiles to grow and survive, thus screening of extremophiles from the deep sea is conducive to the green and sustainable development of industry. In this paper, the application status and problems of genetically engineered strains are reviewed based on the microorganisms needed for extreme industry. This paper focuses on the application status and advantages of deep-sea microorganisms. It is found that their advantages are strong adaptability, stable gene, friendly environment, simple and convenient technology (compared with genetic engineering), which has a broad industry processes application prospect. This review broadens the scope of microbial applications.

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来源期刊
World journal of microbiology & biotechnology
World journal of microbiology & biotechnology 工程技术-生物工程与应用微生物
CiteScore
6.30
自引率
2.40%
发文量
257
审稿时长
2.5 months
期刊介绍: World Journal of Microbiology and Biotechnology publishes research papers and review articles on all aspects of Microbiology and Microbial Biotechnology. Since its foundation, the Journal has provided a forum for research work directed toward finding microbiological and biotechnological solutions to global problems. As many of these problems, including crop productivity, public health and waste management, have major impacts in the developing world, the Journal especially reports on advances for and from developing regions. Some topics are not within the scope of the Journal. Please do not submit your manuscript if it falls into one of the following categories: · Virology · Simple isolation of microbes from local sources · Simple descriptions of an environment or reports on a procedure · Veterinary, agricultural and clinical topics in which the main focus is not on a microorganism · Data reporting on host response to microbes · Optimization of a procedure · Description of the biological effects of not fully identified compounds or undefined extracts of natural origin · Data on not fully purified enzymes or procedures in which they are applied All articles published in the Journal are independently refereed.
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