成功重复使用病原体吸附生物仿生装置辅助治疗 SARS-CoV-2 再感染和不同多重耐药菌的后续感染。

IF 0.7 Q4 UROLOGY & NEPHROLOGY

Case Reports in Nephrology and Dialysis Pub Date : 2024-10-17 eCollection Date: 2024-01-01 DOI:10.1159/000541422

Reuben Okioma, Khalida Soki, Alexander Hay, Jan T Kielstein

{"title":"成功重复使用病原体吸附生物仿生装置辅助治疗 SARS-CoV-2 再感染和不同多重耐药菌的后续感染。","authors":"Reuben Okioma, Khalida Soki, Alexander Hay, Jan T Kielstein","doi":"10.1159/000541422","DOIUrl":null,"url":null,"abstract":"Introduction: The Seraph® 100 Microbind® Affinity Filter is a biomimetic adsorbent device that can remove pathogens from the blood.Case presentation: Here, we report the successful use of the Seraph® 100 to treat both a SARS-CoV-2 reinfection leading to severe COVID-19 pneumonia as well as subsequent secondary lung infections including Acinetobacter baumannii, Serratia marcescens, and Pseudomonas aeruginosa multidrug-resistant bacteria. To our knowledge, this 46-year-old black male is the first patient in which four treatments with this pathogen adsorber, one for a viral and three for different bacterial infections, have been successfully used.Conclusion: The Seraph® 100 can be easily and successfully used in conjunction with standard (anti-infective) treatment.","PeriodicalId":9599,"journal":{"name":"Case Reports in Nephrology and Dialysis","volume":"14 1","pages":"171-177"},"PeriodicalIF":0.7000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521500/pdf/","citationCount":"0","resultStr":"{\"title\":\"Successful Repeated Use of a Pathogen Adsorbing Biomimetic Device for the Adjunct Treatment of a SARS-CoV-2 Reinfection and Subsequent Infections with Different Multiresistant Bacteria.\",\"authors\":\"Reuben Okioma, Khalida Soki, Alexander Hay, Jan T Kielstein\",\"doi\":\"10.1159/000541422\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction: The Seraph® 100 Microbind® Affinity Filter is a biomimetic adsorbent device that can remove pathogens from the blood.Case presentation: Here, we report the successful use of the Seraph® 100 to treat both a SARS-CoV-2 reinfection leading to severe COVID-19 pneumonia as well as subsequent secondary lung infections including Acinetobacter baumannii, Serratia marcescens, and Pseudomonas aeruginosa multidrug-resistant bacteria. To our knowledge, this 46-year-old black male is the first patient in which four treatments with this pathogen adsorber, one for a viral and three for different bacterial infections, have been successfully used.Conclusion: The Seraph® 100 can be easily and successfully used in conjunction with standard (anti-infective) treatment.\",\"PeriodicalId\":9599,\"journal\":{\"name\":\"Case Reports in Nephrology and Dialysis\",\"volume\":\"14 1\",\"pages\":\"171-177\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2024-10-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11521500/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Case Reports in Nephrology and Dialysis\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1159/000541422\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q4\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Case Reports in Nephrology and Dialysis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1159/000541422","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q4","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}

引用次数: 0

摘要

简介Seraph® 100 Microbind® 亲和过滤器是一种仿生物吸附装置，可以清除血液中的病原体：在此，我们报告了使用Seraph® 100成功治疗SARS-CoV-2再感染导致的严重COVID-19肺炎，以及随后的继发性肺部感染，包括鲍曼不动杆菌、肉豆蔻沙雷氏菌和铜绿假单胞菌等多重耐药菌。据我们所知，这位 46 岁的黑人男性是第一位成功使用这种病原体吸附器进行四次治疗的患者，其中一次用于病毒感染，三次用于不同的细菌感染：结论：Seraph® 100 可以与标准（抗感染）治疗轻松、成功地结合使用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Successful Repeated Use of a Pathogen Adsorbing Biomimetic Device for the Adjunct Treatment of a SARS-CoV-2 Reinfection and Subsequent Infections with Different Multiresistant Bacteria.

Introduction: The Seraph^® 100 Microbind^® Affinity Filter is a biomimetic adsorbent device that can remove pathogens from the blood.

Case presentation: Here, we report the successful use of the Seraph^® 100 to treat both a SARS-CoV-2 reinfection leading to severe COVID-19 pneumonia as well as subsequent secondary lung infections including Acinetobacter baumannii, Serratia marcescens, and Pseudomonas aeruginosa multidrug-resistant bacteria. To our knowledge, this 46-year-old black male is the first patient in which four treatments with this pathogen adsorber, one for a viral and three for different bacterial infections, have been successfully used.

Conclusion: The Seraph^® 100 can be easily and successfully used in conjunction with standard (anti-infective) treatment.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Case Reports in Nephrology and Dialysis UROLOGY & NEPHROLOGY-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： This peer-reviewed online-only journal publishes original case reports covering the entire spectrum of nephrology and dialysis, including genetic susceptibility, clinical presentation, diagnosis, treatment or prevention, toxicities of therapy, critical care, supportive care, quality-of-life and survival issues. The journal will also accept case reports dealing with the use of novel technologies, both in the arena of diagnosis and treatment. Supplementary material is welcomed.