{"title":"连接组学革命:利用静息状态 fMRI 和 DTI 对神经和心理认知障碍进行个性化治疗","authors":"Dr Jacky Yeung","doi":"10.1016/j.jmir.2024.101467","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Connectomics has been instrumental in advancing our understanding of the intricate neural networks that underpin neurological and psychiatric conditions. Resting state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) are critical imaging modalities that provide insights into the brain's functional and structural connectivity without the need for active patient participation.</div></div><div><h3>Purpose</h3><div>This presentation is designed to showcase the pivotal role of rs-fMRI and DTI in the burgeoning field of personalized functional imaging. It will highlight how these techniques can redefine the practice of radiological technologists by integrating connectomic insights into personalized patient care.</div></div><div><h3>Methods</h3><div>The presentation will discuss the protocols for employing rs-fMRI and DTI in a clinical environment, including data collection, analysis, and interpretation strategies. It will illustrate the connectome's relevance in various neurological conditions and the ways in which these imaging techniques can contribute to the development of individualized treatment plans.</div></div><div><h3>Results</h3><div>Employing rs-fMRI and DTI for connectomic analysis has yielded promising results in pinpointing neurological disease biomarkers, deciphering psychiatric disorder pathways, and crafting tailored therapeutic interventions. These imaging modalities offer a refined perspective on brain disorders, shifting the diagnostic paradigm from a general to a more patient-centered approach.</div></div><div><h3>Conclusion</h3><div>The integration of connectomics with personalized functional imaging marks a significant advancement in the field of medical imaging. Rs-fMRI and DTI not only enhance our visualization of brain networks but also support a transition toward treatments aimed at the underlying mechanisms of disease. Embracing these techniques is crucial for the progression of personalized medicine and the enhancement of patient care outcomes.</div></div><div><h3>Implications</h3><div>The keynote will delve into the implications of these technologies for radiological technologists, stressing the necessity for a transition to a connectome-based imaging model. Additionally, it will touch upon the educational and skill development needed for practitioners to adeptly adopt and apply these sophisticated imaging techniques in a personalized healthcare setting.</div></div>","PeriodicalId":46420,"journal":{"name":"Journal of Medical Imaging and Radiation Sciences","volume":null,"pages":null},"PeriodicalIF":1.3000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The connectomics revolution: Utilizing Resting State fMRI and DTI to personalize the treatment of neurological and psychocognitive disorders\",\"authors\":\"Dr Jacky Yeung\",\"doi\":\"10.1016/j.jmir.2024.101467\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Connectomics has been instrumental in advancing our understanding of the intricate neural networks that underpin neurological and psychiatric conditions. Resting state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) are critical imaging modalities that provide insights into the brain's functional and structural connectivity without the need for active patient participation.</div></div><div><h3>Purpose</h3><div>This presentation is designed to showcase the pivotal role of rs-fMRI and DTI in the burgeoning field of personalized functional imaging. It will highlight how these techniques can redefine the practice of radiological technologists by integrating connectomic insights into personalized patient care.</div></div><div><h3>Methods</h3><div>The presentation will discuss the protocols for employing rs-fMRI and DTI in a clinical environment, including data collection, analysis, and interpretation strategies. It will illustrate the connectome's relevance in various neurological conditions and the ways in which these imaging techniques can contribute to the development of individualized treatment plans.</div></div><div><h3>Results</h3><div>Employing rs-fMRI and DTI for connectomic analysis has yielded promising results in pinpointing neurological disease biomarkers, deciphering psychiatric disorder pathways, and crafting tailored therapeutic interventions. These imaging modalities offer a refined perspective on brain disorders, shifting the diagnostic paradigm from a general to a more patient-centered approach.</div></div><div><h3>Conclusion</h3><div>The integration of connectomics with personalized functional imaging marks a significant advancement in the field of medical imaging. Rs-fMRI and DTI not only enhance our visualization of brain networks but also support a transition toward treatments aimed at the underlying mechanisms of disease. Embracing these techniques is crucial for the progression of personalized medicine and the enhancement of patient care outcomes.</div></div><div><h3>Implications</h3><div>The keynote will delve into the implications of these technologies for radiological technologists, stressing the necessity for a transition to a connectome-based imaging model. Additionally, it will touch upon the educational and skill development needed for practitioners to adeptly adopt and apply these sophisticated imaging techniques in a personalized healthcare setting.</div></div>\",\"PeriodicalId\":46420,\"journal\":{\"name\":\"Journal of Medical Imaging and Radiation Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.3000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Medical Imaging and Radiation Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S193986542400198X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Medical Imaging and Radiation Sciences","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S193986542400198X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
The connectomics revolution: Utilizing Resting State fMRI and DTI to personalize the treatment of neurological and psychocognitive disorders
Background
Connectomics has been instrumental in advancing our understanding of the intricate neural networks that underpin neurological and psychiatric conditions. Resting state functional magnetic resonance imaging (rs-fMRI) and diffusion tensor imaging (DTI) are critical imaging modalities that provide insights into the brain's functional and structural connectivity without the need for active patient participation.
Purpose
This presentation is designed to showcase the pivotal role of rs-fMRI and DTI in the burgeoning field of personalized functional imaging. It will highlight how these techniques can redefine the practice of radiological technologists by integrating connectomic insights into personalized patient care.
Methods
The presentation will discuss the protocols for employing rs-fMRI and DTI in a clinical environment, including data collection, analysis, and interpretation strategies. It will illustrate the connectome's relevance in various neurological conditions and the ways in which these imaging techniques can contribute to the development of individualized treatment plans.
Results
Employing rs-fMRI and DTI for connectomic analysis has yielded promising results in pinpointing neurological disease biomarkers, deciphering psychiatric disorder pathways, and crafting tailored therapeutic interventions. These imaging modalities offer a refined perspective on brain disorders, shifting the diagnostic paradigm from a general to a more patient-centered approach.
Conclusion
The integration of connectomics with personalized functional imaging marks a significant advancement in the field of medical imaging. Rs-fMRI and DTI not only enhance our visualization of brain networks but also support a transition toward treatments aimed at the underlying mechanisms of disease. Embracing these techniques is crucial for the progression of personalized medicine and the enhancement of patient care outcomes.
Implications
The keynote will delve into the implications of these technologies for radiological technologists, stressing the necessity for a transition to a connectome-based imaging model. Additionally, it will touch upon the educational and skill development needed for practitioners to adeptly adopt and apply these sophisticated imaging techniques in a personalized healthcare setting.
期刊介绍:
Journal of Medical Imaging and Radiation Sciences is the official peer-reviewed journal of the Canadian Association of Medical Radiation Technologists. This journal is published four times a year and is circulated to approximately 11,000 medical radiation technologists, libraries and radiology departments throughout Canada, the United States and overseas. The Journal publishes articles on recent research, new technology and techniques, professional practices, technologists viewpoints as well as relevant book reviews.