动物源食品和环境样本中硝基呋喃及其代谢物的预处理和检测方法综述

IF 6.5 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry: X Pub Date : 2024-10-28 DOI:10.1016/j.fochx.2024.101928

Xiaoling Zheng , Yong Xie , Zhuoer Chen , Mingdong Cao , Xianlu Lei , Tao Le

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引用次数: 0

摘要

近年来，动物源性食品和环境样本中的硝基呋喃（NFs）及其代谢物残留问题受到广泛关注。硝基呋喃类药物及其代谢物对人类健康有显著毒性，包括致癌、致突变和致畸作用，导致许多国家禁止在畜牧业中使用硝基呋喃类药物。因此，为了保证公众健康和生态安全，有必要对 NFs 的残留进行监测。本综述旨在总结和评估动物源食品和环境样品中 NFs 及其代谢物的结构特性、残留状况、样品前处理方法（液液萃取、固相萃取、快速、简便、廉价、有效、坚固和安全（QuEChERS）和现场辅助萃取）和检测方法（色谱分析、免疫测定和一些创新的检测方法）。本文对 NFs 及其代谢物的分析进行了详细的参考和讨论，可有效促进 NFs 及其代谢物残留的创新检测方法的建立。

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A comprehensive review on the pretreatment and detection methods of nitrofurans and their metabolites in animal-derived food and environmental samples

In recent years, the residues of nitrofurans (NFs) and their metabolites in animal-derived food and environmental samples have gained widespread attention. The parent drugs and their metabolites have displayed significant toxicity to human health including carcinogenic, mutagenic and teratogenic effects, leading to banned in animal husbandry in many countries. Hence, monitoring the residues of NFs is necessary to guarantee public health and ecological security. This review aims to summarize and assess the structural properties, residue status, sample pretreatment methods (liquid-liquid extraction, solid-phase extraction, Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS), and field-assisted extraction), and detection methods (chromatographic analysis, immunoassay, and some innovative detection methods) for NFs and their metabolites in animal-derived food and environmental samples. This paper provides a detailed reference and discussion for the analysis of NFs and their metabolites, which can effectively promote the establishment of innovative detection methods for NFs and their metabolites residues.

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来源期刊

Food Chemistry: X CHEMISTRY, APPLIED-

CiteScore

4.90

自引率

6.60%

发文量

315

审稿时长

55 days

期刊介绍： Food Chemistry: X, one of three Open Access companion journals to Food Chemistry, follows the same aims, scope, and peer-review process. It focuses on papers advancing food and biochemistry or analytical methods, prioritizing research novelty. Manuscript evaluation considers novelty, scientific rigor, field advancement, and reader interest. Excluded are studies on food molecular sciences or disease cure/prevention. Topics include food component chemistry, bioactives, processing effects, additives, contaminants, and analytical methods. The journal welcome Analytical Papers addressing food microbiology, sensory aspects, and more, emphasizing new methods with robust validation and applicability to diverse foods or regions.