在一名中国人身上通过基于测序的分型鉴定出一个新的 HLA-B*15 变异等位基因 HLA-B*15:359。

IF 5.9 4区 医学 Q2 CELL BIOLOGY
HLA Pub Date : 2024-10-29 DOI:10.1111/tan.15745
Xiao-Feng Li, Xu Zhang, Feng-Qiu Lin, Jian-Ping Li
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引用次数: 0

摘要

HLA-B*15:359 与 HLA-B*15:01:01:01 的区别在于外显子 3 中的一个核苷酸替换。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel HLA-B*15 Variant Allele, HLA-B*15:359, Identified by Sequencing-Based Typing in a Chinese Individual

HLA-B*15:359 differs from HLA-B*15:01:01:01 by one nucleotide substitution in exon 3.

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来源期刊
HLA
HLA Immunology and Microbiology-Immunology
CiteScore
3.00
自引率
28.80%
发文量
368
期刊介绍: HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.
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