68Ga-FAPI-46 PET/CT 上的胆囊生理性积聚。

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2024-12-01 Epub Date: 2024-10-10 DOI:10.1097/RLU.0000000000005480

Ömer Faruk Şahin, Göksel Alçın, Nurhan Ergül, Tevfik Fikret Çermik, Esra Arslan

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引用次数: 0

摘要

摘要：放射性标记成纤维细胞活化蛋白抑制剂（FAPIs）是检测和治疗癌症的一种新方法。FAPI 以成纤维细胞活化蛋白为靶标，成纤维细胞活化蛋白由癌症相关成纤维细胞大量产生，在肿瘤发生发展过程中起着关键作用。与传统方法相比，FAPI 先进的成像功能可提供更清晰的实体瘤成像结果，因此在肿瘤学领域备受关注。此外，FAPI 在动脉粥样硬化和关节炎等需要组织重塑的病症中的活性也凸显了其更广泛的潜力。这张有趣的图片显示了 68Ga-FAPI 在胆囊中的生理性积聚，强调了准确解读对防止误诊和确保有效管理病人的重要性。

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Physiological Gallbladder Accumulation on 68 Ga-FAPI-46 PET/CT.

Abstract: Radiolabeled fibroblast activation protein inhibitors (FAPIs) are a novel approach in cancer detection and treatment. Targeting fibroblast activation protein, extensively produced by cancer-associated fibroblasts, FAPI plays a key role in tumor development. Its advanced imaging capabilities offer clearer results in solid tumors compared with traditional methods, drawing significant interest in oncology. Additionally, FAPI's activity in conditions requiring tissue remodeling, such as atherosclerosis and arthritis, highlights its broader potential. This interesting image shows the physiological accumulation of 68 Ga-FAPI in the gallbladder, emphasizing the importance of accurate interpretation to prevent misdiagnoses and ensure effective patient management.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.