拮抗 CLE 肽途径塑造根分生组织模式

IF 15.8 1区 生物学 Q1 PLANT SCIENCES
Hang Zhang, Qian Wang, Noel Blanco-Touriñán, Christian S. Hardtke
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引用次数: 0

摘要

分泌的 CLAVATA3/EMBRYO SURROUNDING REGION(CLE)肽配体通过冗余和交叉补偿的 CLAVATA1(CLV1)型受体激酶发出信号,对拟南芥芽分生组织的干细胞龛进行维度调节。在根分生组织中,CLV1 的同源物 BARELY ANY MERISTEM 1(BAM1)和 BAM2 驱动 CLE13/16 介导的形成分裂,产生地面组织层。在这里,我们报告了 BAM1/2 也是启动维管韧皮部的必要条件,而且在芽中观察到的 CLV1 型受体之间的交叉补偿在根中并没有类似的作用。相反,我们发现 BAM3 介导的 CLE45 信号能拮抗 BAM1/2 介导的 CLE11/12/13 信号,但在韧皮部初始组织中却不能。我们进一步观察到,韧皮部的萌发和分化对 CLE 信号的要求在时空上形成鲜明对比,而这些要求是由短根(SHR)途径形成的。因此,我们的研究结果表明,在拟南芥根分生组织中,不同的、相互拮抗的 CLE 信号通路之间存在着错综复杂的定量相互作用,从而组织了组织层的形成。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Antagonistic CLE peptide pathways shape root meristem tissue patterning

Antagonistic CLE peptide pathways shape root meristem tissue patterning

Secreted CLAVATA3/EMBRYO SURROUNDING REGION (CLE) peptide ligands dimension the stem cell niche of Arabidopsis shoot meristems by signalling through redundant and cross-compensating CLAVATA1 (CLV1)-type receptor kinases. In the root meristem, the CLV1 homologues BARELY ANY MERISTEM 1 (BAM1) and BAM2 drive CLE13/16-mediated formative divisions that produce the ground tissue layers. Here we report that BAM1/2 are also required to initiate the vascular phloem lineage and that cross-compensation between CLV1-type receptors as observed in the shoot does not operate similarly in the root. Rather, we find that BAM3-mediated CLE45 signalling antagonizes BAM1/2-mediated CLE11/12/13 signalling in the phloem initials but not in the ground tissue. We further observe spatiotemporally contrasting CLE signalling requirements for phloem initiation and differentiation, which are shaped by the SHORT ROOT (SHR) pathway. Our findings thus suggest an intricate quantitative interplay between distinct and antagonistic CLE signalling pathways that organizes tissue layer formation in the Arabidopsis root meristem.

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来源期刊
Nature Plants
Nature Plants PLANT SCIENCES-
CiteScore
25.30
自引率
2.20%
发文量
196
期刊介绍: Nature Plants is an online-only, monthly journal publishing the best research on plants — from their evolution, development, metabolism and environmental interactions to their societal significance.
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