4,6-取代的 2-叠氮嘧啶的叠氮-四氮唑重排的动力学和热力学特征

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2024-10-26 DOI:10.1007/s11172-024-4372-x

N. V. Aleksandrova, E. B. Nikolaenkova, V. I. Mamatyuk, V. P. Krivopalov

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引用次数: 0

摘要

利用核磁共振光谱法研究了一系列取代的 2-叠氮基嘧啶的叠氮化四氮唑同分异构体。确定了溶液中存在的同分异构体的结构。通过改变温度，从 NOESY/EXSY 光谱中的综合信号强度确定了所研究的同分异构体的活化参数。研究发现，苯基取代基加速了同分异构体的转化。

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Kinetic and thermodynamic characteristics of the azide-tetrazole rearrangement of 4,6-substituted 2-azidopyrimidines

Azide-tetrazole tautomerism in a series of substituted 2-azidopyrimidines were studied by NMR spectroscopy methods. The structures of the tautomers existing in a solution were determined. By varying the temperature, the activation parameters of the studied tautomerism were determined from the integrated signal intensity in the NOESY/EXSY spectra. It was found that the phenyl substituents accelerate the tautomeric transformations.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.