A. E. Margaryan, I. A. Platonov, I. N. Kolesnichenko, E. A. Novikova, A. S. Karsunkina
{"title":"基于 Silagerm 8040 的平面微流控芯片，用于气体介质分析中的取样和样品制备","authors":"A. E. Margaryan, I. A. Platonov, I. N. Kolesnichenko, E. A. Novikova, A. S. Karsunkina","doi":"10.1134/S1061934824700758","DOIUrl":null,"url":null,"abstract":"<p>A technology is developed for manufacturing planar microfluidic chips (MFCs) based on Silgard 8040, encompassing template fabrication, mold production, sealing, and adsorbent filling. These MFCs, filled with a Porapak-Q adsorbent, facilitate sample preparation and calibration under uniform conditions, integrating both sample collection and preconcentration stages. Experimental investigations have identified optimal conditions for acetone preconcentration using Silgard 8040-based MFCs, achieving a maximum concentration factor of 43 at adsorption temperature (<i>T</i><sub>ads</sub>) of 0°C, desorption temperature (<i>T</i><sub>des</sub>) of 70°C, adsorption volume (<i>V</i><sub>ads</sub>) of 45 mL, and desorption time (<i>t</i><sub>des</sub>) of 1 s. The feasibility of using MFCs for sample collection and preparation, taking into account sample storage time, has been evaluated. The procedure maintains accuracy within 6–10% over 8 h without a necessity for additional drying of the collected samples from exhaled air.</p>","PeriodicalId":606,"journal":{"name":"Journal of Analytical Chemistry","volume":null,"pages":null},"PeriodicalIF":1.0000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Silagerm 8040-Based Planar Microfluidic Chips for Sampling and Sample Preparation in the Analysis of Gas Media\",\"authors\":\"A. E. Margaryan, I. A. Platonov, I. N. Kolesnichenko, E. A. Novikova, A. S. Karsunkina\",\"doi\":\"10.1134/S1061934824700758\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>A technology is developed for manufacturing planar microfluidic chips (MFCs) based on Silgard 8040, encompassing template fabrication, mold production, sealing, and adsorbent filling. These MFCs, filled with a Porapak-Q adsorbent, facilitate sample preparation and calibration under uniform conditions, integrating both sample collection and preconcentration stages. Experimental investigations have identified optimal conditions for acetone preconcentration using Silgard 8040-based MFCs, achieving a maximum concentration factor of 43 at adsorption temperature (<i>T</i><sub>ads</sub>) of 0°C, desorption temperature (<i>T</i><sub>des</sub>) of 70°C, adsorption volume (<i>V</i><sub>ads</sub>) of 45 mL, and desorption time (<i>t</i><sub>des</sub>) of 1 s. The feasibility of using MFCs for sample collection and preparation, taking into account sample storage time, has been evaluated. The procedure maintains accuracy within 6–10% over 8 h without a necessity for additional drying of the collected samples from exhaled air.</p>\",\"PeriodicalId\":606,\"journal\":{\"name\":\"Journal of Analytical Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.0000,\"publicationDate\":\"2024-10-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Analytical Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1134/S1061934824700758\",\"RegionNum\":4,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"CHEMISTRY, ANALYTICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Analytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1061934824700758","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ANALYTICAL","Score":null,"Total":0}
Silagerm 8040-Based Planar Microfluidic Chips for Sampling and Sample Preparation in the Analysis of Gas Media
A technology is developed for manufacturing planar microfluidic chips (MFCs) based on Silgard 8040, encompassing template fabrication, mold production, sealing, and adsorbent filling. These MFCs, filled with a Porapak-Q adsorbent, facilitate sample preparation and calibration under uniform conditions, integrating both sample collection and preconcentration stages. Experimental investigations have identified optimal conditions for acetone preconcentration using Silgard 8040-based MFCs, achieving a maximum concentration factor of 43 at adsorption temperature (Tads) of 0°C, desorption temperature (Tdes) of 70°C, adsorption volume (Vads) of 45 mL, and desorption time (tdes) of 1 s. The feasibility of using MFCs for sample collection and preparation, taking into account sample storage time, has been evaluated. The procedure maintains accuracy within 6–10% over 8 h without a necessity for additional drying of the collected samples from exhaled air.
期刊介绍：
The Journal of Analytical Chemistry is an international peer reviewed journal that covers theoretical and applied aspects of analytical chemistry; it informs the reader about new achievements in analytical methods, instruments and reagents. Ample space is devoted to problems arising in the analysis of vital media such as water and air. Consideration is given to the detection and determination of metal ions, anions, and various organic substances. The journal welcomes manuscripts from all countries in the English or Russian language.
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