空气污染与骨矿物质密度之间的关系：孟德尔随机研究。

IF 3 4区医学 Q1 MEDICINE, GENERAL & INTERNAL

Archives of Medical Science Pub Date : 2024-08-28 eCollection Date: 2024-01-01 DOI:10.5114/aoms/192628

Rui Jiang, Qi Qu, Zhiyu Wang, Feng Luo, Shuanglin Mou

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引用次数: 0

摘要

简介：空气污染与骨矿物质密度（BMD）的关系日益受到关注。然而，因果关系的确定仍不确定：方法：我们进行了一项孟德尔随机化（MR）研究，以 PM2.5、PM2.5-10、PM10、二氧化氮和氮氧化物为暴露因子，以骨矿物质密度为结果，探讨空气污染与骨矿物质密度下降之间的因果关系：通过采用 IVW 方法，我们发现空气污染（PM2.5、PM10 和氮氧化物）与 BMD 之间存在负因果关系：我们的研究结果表明，接触 PM2.5、PM10 和氮氧化物可能会导致 BMD 下降。

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Association between air pollution and bone mineral density: a Mendelian randomization study.

Introduction: The association of air pollution with bone mineral density (BMD) has attracted increasing attention. However, establishing a causal relationship remains uncertain.

Methods: We conducted a Mendelian randomization (MR) study employing PM_2.5, PM_2.5-10, PM₁₀, nitrogen dioxide, and nitrogen oxides as exposures and BMD as the outcome to explore the causality between air pollution and the occurrence of decreased BMD.

Results: By employing the IVW method, we identified a negative causality between air pollution (PM_2.5, PM₁₀, and nitrogen oxides) and BMD.

Conclusions: Our findings demonstrate that PM_2.5, PM₁₀ and nitrogen oxides exposure may contribute to decreased BMD.

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来源期刊

Archives of Medical Science 医学-医学：内科

CiteScore

4.90

自引率

7.90%

发文量

139

审稿时长

1.7 months

期刊介绍： Archives of Medical Science (AMS) publishes high quality original articles and reviews of recognized scientists that deal with all scientific medicine. AMS opens the possibilities for young, capable scientists. The journal would like to give them a chance to have a publication following matter-of-fact, professional review by outstanding, famous medical scientists. Thanks to that they will have an opportunity to present their study results and/or receive useful advice about the mistakes they have made so far. The second equally important aim is a presentation of review manuscripts of recognized scientists about the educational capacity, in order that young scientists, often at the beginning of their scientific carrier, could constantly deepen their medical knowledge and be up-to-date with current guidelines and trends in world-wide medicine. The fact that our educational articles are written by world-famous scientists determines their innovation and the highest quality.