在野外条件下接种大肠杆菌、A/C 型产气荚膜杆菌疫苗对仔猪生产性能和临床指标的影响

IF 5.2 3区 医学 Q1 IMMUNOLOGY
Vaccines Pub Date : 2024-10-17 DOI:10.3390/vaccines12101185
Arkadiusz Dors, Robert Panek, Wojciech Łużyński, Krzysztof Janeczko, Agata Augustyniak, Hanna Turlewicz-Podbielska, Ewelina Czyżewska-Dors, Małgorzata Pomorska-Mól
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引用次数: 0

摘要

背景:控制新生猪腹泻(NPD)的主要策略之一是给母猪接种疫苗。本研究旨在比较两种商业疫苗接种方案在一个猪场实地条件下的效果,该猪场的 A 型 cpb2 阳性菌株与 NPD 有牵连。方法:这项研究是在一个拥有 5500 头母猪的产仔至断奶猪群中进行的,该猪群已使用大肠杆菌和产气荚膜杆菌疫苗,但仍患有 NPD。在确认存在 A 型 cpb2 阳性菌株的情况下,按照生产商的说明给 A 组母猪注射 Enteroporc Coli AC®(Ceva)。B 组母猪接种的是另外两种商用联合疫苗。每组都对 10 窝仔猪进行耳标测量,并分别在出生时、8 日龄和 22 日龄时称重。记录仔猪出生后连续 10 天内的腹泻发生率、总体体况和抗菌治疗情况。结果共纳入 234 头仔猪(A 组 119 头,B 组 115 头)。仔猪从出生到 22 日龄的平均增重,A 组(4.99 千克)明显高于 B 组(4.66 千克)(p = 0.039)。记录的其他参数,如是否腹泻、仔猪体况评分和使用抗菌药治疗的天数在各组之间没有显著差异。结论本研究证实,肠道大肠杆菌 AC® 疫苗可有效减少仔猪腹泻的临床症状,其效果与本研究中使用的其他疫苗相当。研究还观察到了疫苗对哺乳期仔猪生产性能的积极影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Vaccination Against E. coli, C. perfringens Type A/C on Piglet Productive and Clinical Parameters Under Field Conditions.

Background: One of the main strategies to control neonatal porcine diarrhoea (NPD) is through vaccination of the sows. This study aimed to compare the efficacy of two commercial vaccination schemes under field conditions on a farm where a C. perfringens type A cpb2-positive strain was implicated in NPD. Methods: This study was performed in a farrow-to-wean herd with 5500 sows, already using an E. coli and C. perfringens vaccine but still suffering NPD. Where the presence of a C. perfringens type A cpb2-positive strain was confirmed, Enteroporc Coli AC® (Ceva) was administrated to the sows in group A according to the manufacturer's instructions. Sows in group B were vaccinated using two other combined commercial vaccines. In each group, piglets from 10 litters were ear-tagged and individually weighed at birth and at 8 and 22 days of age. The incidence of diarrhoea, general piglet body condition, and antimicrobial treatment were recorded within 10 consecutive days after birth. Results: A total of 234 piglets (119 in group A and 115 in group B) were included. The mean weight gain of piglets from birth to 22 days of age was significantly higher in group A (4.99 kg) than in group B (4.66 kg) (p = 0.039). The rest of the recorded parameters such as the presence of diarrhoea, the piglet's body condition score, and the number of days with antimicrobial treatment did not differ significantly between groups. Conclusions: This study confirmed the efficiency of the Enteroporc Coli AC® vaccine in reducing clinical symptoms of diarrhoea in piglets, which was comparable with the other vaccines used in the study. The positive effect on piglets' productive performance during the lactation phase was observed.

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来源期刊
Vaccines
Vaccines Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
8.90
自引率
16.70%
发文量
1853
审稿时长
18.06 days
期刊介绍: Vaccines (ISSN 2076-393X) is an international, peer-reviewed open access journal focused on laboratory and clinical vaccine research, utilization and immunization. Vaccines publishes high quality reviews, regular research papers, communications and case reports.
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