Arkadiusz Dors, Robert Panek, Wojciech Łużyński, Krzysztof Janeczko, Agata Augustyniak, Hanna Turlewicz-Podbielska, Ewelina Czyżewska-Dors, Małgorzata Pomorska-Mól
{"title":"在野外条件下接种大肠杆菌、A/C 型产气荚膜杆菌疫苗对仔猪生产性能和临床指标的影响","authors":"Arkadiusz Dors, Robert Panek, Wojciech Łużyński, Krzysztof Janeczko, Agata Augustyniak, Hanna Turlewicz-Podbielska, Ewelina Czyżewska-Dors, Małgorzata Pomorska-Mól","doi":"10.3390/vaccines12101185","DOIUrl":null,"url":null,"abstract":"<p><p><b>Background</b>: One of the main strategies to control neonatal porcine diarrhoea (NPD) is through vaccination of the sows. This study aimed to compare the efficacy of two commercial vaccination schemes under field conditions on a farm where a <i>C. perfringens</i> type A <i>cpb2</i>-positive strain was implicated in NPD. <b>Methods</b>: This study was performed in a farrow-to-wean herd with 5500 sows, already using an <i>E. coli</i> and <i>C. perfringens</i> vaccine but still suffering NPD. Where the presence of a <i>C. perfringens</i> type A <i>cpb2</i>-positive strain was confirmed, Enteroporc Coli AC<sup>®</sup> (Ceva) was administrated to the sows in group A according to the manufacturer's instructions. Sows in group B were vaccinated using two other combined commercial vaccines. In each group, piglets from 10 litters were ear-tagged and individually weighed at birth and at 8 and 22 days of age. The incidence of diarrhoea, general piglet body condition, and antimicrobial treatment were recorded within 10 consecutive days after birth. <b>Results</b>: A total of 234 piglets (119 in group A and 115 in group B) were included. The mean weight gain of piglets from birth to 22 days of age was significantly higher in group A (4.99 kg) than in group B (4.66 kg) (<i>p</i> = 0.039). The rest of the recorded parameters such as the presence of diarrhoea, the piglet's body condition score, and the number of days with antimicrobial treatment did not differ significantly between groups. <b>Conclusions</b>: This study confirmed the efficiency of the Enteroporc Coli AC<sup>®</sup> vaccine in reducing clinical symptoms of diarrhoea in piglets, which was comparable with the other vaccines used in the study. The positive effect on piglets' productive performance during the lactation phase was observed.</p>","PeriodicalId":23634,"journal":{"name":"Vaccines","volume":"12 10","pages":""},"PeriodicalIF":5.2000,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511424/pdf/","citationCount":"0","resultStr":"{\"title\":\"Effect of Vaccination Against <i>E. coli</i>, <i>C. perfringens</i> Type A/C on Piglet Productive and Clinical Parameters Under Field Conditions.\",\"authors\":\"Arkadiusz Dors, Robert Panek, Wojciech Łużyński, Krzysztof Janeczko, Agata Augustyniak, Hanna Turlewicz-Podbielska, Ewelina Czyżewska-Dors, Małgorzata Pomorska-Mól\",\"doi\":\"10.3390/vaccines12101185\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p><b>Background</b>: One of the main strategies to control neonatal porcine diarrhoea (NPD) is through vaccination of the sows. This study aimed to compare the efficacy of two commercial vaccination schemes under field conditions on a farm where a <i>C. perfringens</i> type A <i>cpb2</i>-positive strain was implicated in NPD. <b>Methods</b>: This study was performed in a farrow-to-wean herd with 5500 sows, already using an <i>E. coli</i> and <i>C. perfringens</i> vaccine but still suffering NPD. Where the presence of a <i>C. perfringens</i> type A <i>cpb2</i>-positive strain was confirmed, Enteroporc Coli AC<sup>®</sup> (Ceva) was administrated to the sows in group A according to the manufacturer's instructions. Sows in group B were vaccinated using two other combined commercial vaccines. In each group, piglets from 10 litters were ear-tagged and individually weighed at birth and at 8 and 22 days of age. The incidence of diarrhoea, general piglet body condition, and antimicrobial treatment were recorded within 10 consecutive days after birth. <b>Results</b>: A total of 234 piglets (119 in group A and 115 in group B) were included. The mean weight gain of piglets from birth to 22 days of age was significantly higher in group A (4.99 kg) than in group B (4.66 kg) (<i>p</i> = 0.039). The rest of the recorded parameters such as the presence of diarrhoea, the piglet's body condition score, and the number of days with antimicrobial treatment did not differ significantly between groups. <b>Conclusions</b>: This study confirmed the efficiency of the Enteroporc Coli AC<sup>®</sup> vaccine in reducing clinical symptoms of diarrhoea in piglets, which was comparable with the other vaccines used in the study. The positive effect on piglets' productive performance during the lactation phase was observed.</p>\",\"PeriodicalId\":23634,\"journal\":{\"name\":\"Vaccines\",\"volume\":\"12 10\",\"pages\":\"\"},\"PeriodicalIF\":5.2000,\"publicationDate\":\"2024-10-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11511424/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vaccines\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3390/vaccines12101185\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vaccines","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3390/vaccines12101185","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Effect of Vaccination Against E. coli, C. perfringens Type A/C on Piglet Productive and Clinical Parameters Under Field Conditions.
Background: One of the main strategies to control neonatal porcine diarrhoea (NPD) is through vaccination of the sows. This study aimed to compare the efficacy of two commercial vaccination schemes under field conditions on a farm where a C. perfringens type A cpb2-positive strain was implicated in NPD. Methods: This study was performed in a farrow-to-wean herd with 5500 sows, already using an E. coli and C. perfringens vaccine but still suffering NPD. Where the presence of a C. perfringens type A cpb2-positive strain was confirmed, Enteroporc Coli AC® (Ceva) was administrated to the sows in group A according to the manufacturer's instructions. Sows in group B were vaccinated using two other combined commercial vaccines. In each group, piglets from 10 litters were ear-tagged and individually weighed at birth and at 8 and 22 days of age. The incidence of diarrhoea, general piglet body condition, and antimicrobial treatment were recorded within 10 consecutive days after birth. Results: A total of 234 piglets (119 in group A and 115 in group B) were included. The mean weight gain of piglets from birth to 22 days of age was significantly higher in group A (4.99 kg) than in group B (4.66 kg) (p = 0.039). The rest of the recorded parameters such as the presence of diarrhoea, the piglet's body condition score, and the number of days with antimicrobial treatment did not differ significantly between groups. Conclusions: This study confirmed the efficiency of the Enteroporc Coli AC® vaccine in reducing clinical symptoms of diarrhoea in piglets, which was comparable with the other vaccines used in the study. The positive effect on piglets' productive performance during the lactation phase was observed.
VaccinesPharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
8.90
自引率
16.70%
发文量
1853
审稿时长
18.06 days
期刊介绍:
Vaccines (ISSN 2076-393X) is an international, peer-reviewed open access journal focused on laboratory and clinical vaccine research, utilization and immunization. Vaccines publishes high quality reviews, regular research papers, communications and case reports.