伯克霍尔德氏菌污染新鲜冰冻血浆导致输血传播细菌感染。

IF 1.9 4区医学 Q3 INFECTIOUS DISEASES

Journal of Infection and Chemotherapy Pub Date : 2024-10-24 DOI:10.1016/j.jiac.2024.10.013

Vithiya G, P Shunmuga Sundaram, T Rajendran

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引用次数: 0

摘要

由于冷冻储存的原因，血浆受到细菌污染的情况并不常见。我们报告了一例因新鲜冰冻血浆污染伯克霍尔德氏菌而导致的输血传播感染病例。一名患有慢性肝病失代偿期的 31 岁男性因胸腔积液出现呼吸困难。由于凝血酶原时间升高，他输注了新鲜冰冻血浆。输注 10 分钟后，他开始发热、心跳过速，输血随即停止。患者的血浆袋和血液培养物中都检出了头孢杆菌。由于潜在的疾病，他的血流动力学变得不稳定，一周后死亡。

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Burkholderia cepacia contaminating fresh frozen plasma causing transfusion transmitted bacterial infection.

Bacterial contamination of plasma is unusual owing to frozen storage nevertheless reported. We report a case of transfusion transmitted infection due to Burkholderia cepacia contaminating fresh frozen plasma. A 31 year old male with decompensated chronic liver disease presented with breathlessness due to pleural effusion. Due to elevated prothrombin time, fresh frozen plasma was infused. After ten minutes of transfusion, he became febrile, tachypnoeic and transfusion was stopped. Plasma bag and blood cultures from patient grew B. cepacia. He became hemodynamically unstable due to underlying disease and died after a week.

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来源期刊

Journal of Infection and Chemotherapy INFECTIOUS DISEASES-PHARMACOLOGY & PHARMACY

CiteScore

4.10

自引率

4.50%

发文量

303

审稿时长

47 days

期刊介绍： The Journal of Infection and Chemotherapy (JIC) — official journal of the Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases — welcomes original papers, laboratory or clinical, as well as case reports, notes, committee reports, surveillance and guidelines from all parts of the world on all aspects of chemotherapy, covering the pathogenesis, diagnosis, treatment, and control of infection, including treatment with anticancer drugs. Experimental studies on animal models and pharmacokinetics, and reports on epidemiology and clinical trials are particularly welcome.