RNA 在生命早期进化中的先锋作用。

IF 1.7 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Genetics and Molecular Biology Pub Date : 2024-09-02 eCollection Date: 2024-01-01 DOI:10.1590/1678-4685-GMB-2024-0028

Israel Muñoz-Velasco, Adrián Cruz-González, Ricardo Hernández-Morales, José Alberto Campillo-Balderas, Wolfgang Cottom-Salas, Rodrigo Jácome, Alberto Vázquez-Salazar

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引用次数: 0

摘要

RNA 的催化、调控和结构特性，以及它们在细胞过程中无处不在的特殊性，与这种分子在生物进化早期阶段在遗传和新陈代谢中发挥着更为显著作用的说法是一致的。这篇综述探讨了 RNA 在最早生命形式中的关键作用及其与现代生物系统的相关性。它探讨了当前研究生命早期进化的模型，提供了对原始 RNA 世界及其在当代生物学中的遗产的见解。

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Pioneering role of RNA in the early evolution of life.

The catalytic, regulatory and structural properties of RNA, combined with their extraordinary ubiquity in cellular processes, are consistent with the proposal that this molecule played a much more conspicuous role in heredity and metabolism during the early stages of biological evolution. This review explores the pivotal role of RNA in the earliest life forms and its relevance in modern biological systems. It examines current models that study the early evolution of life, providing insights into the primordial RNA world and its legacy in contemporary biology.

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来源期刊

Genetics and Molecular Biology 生物-生化与分子生物学

CiteScore

4.20

自引率

4.80%

发文量

111

审稿时长

3 months

期刊介绍： Genetics and Molecular Biology (formerly named Revista Brasileira de Genética/Brazilian Journal of Genetics - ISSN 0100-8455) is published by the Sociedade Brasileira de Genética (Brazilian Society of Genetics). The Journal considers contributions that present the results of original research in genetics, evolution and related scientific disciplines. Manuscripts presenting methods and applications only, without an analysis of genetic data, will not be considered.