{"title":"阿拉伯联合酋长国迪拜的 Elizabethkingia Meningoseptica：一项为期 7 年的多中心研究。","authors":"Hawra Ali Hussain Alsayed, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Rabih Halwani","doi":"10.1016/j.ajic.2024.10.016","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Elizabethkingia meningoseptica (E. meningoseptica) is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly.</p><p><strong>Methods: </strong>This study aimed to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in United Arab Emirates. A retrospective chart review study was conducted at four hospitals that are part of Dubai Academic Health Corporation.</p><p><strong>Results: </strong>A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n = 13, 57%). The in-hospital mortality rate was 38% (n = 5) in adults and 20% (n = 2) in pediatrics.</p><p><strong>Conclusions: </strong>E. meningoseptica is a significant nosocomial pathogen with high antibiotic resistance, posing severe risks to immunocompromised pediatric and adult patients. Effective management of E. meningoseptica requires vigilant monitoring, comprehensive control, and targeted therapies.</p>","PeriodicalId":7621,"journal":{"name":"American journal of infection control","volume":" ","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2024-10-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Elizabethkingia meningoseptica in Dubai, United Arab Emirates: A 7-year multicenter study.\",\"authors\":\"Hawra Ali Hussain Alsayed, Narjes Saheb Sharif-Askari, Fatemeh Saheb Sharif-Askari, Rabih Halwani\",\"doi\":\"10.1016/j.ajic.2024.10.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Elizabethkingia meningoseptica (E. meningoseptica) is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly.</p><p><strong>Methods: </strong>This study aimed to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in United Arab Emirates. A retrospective chart review study was conducted at four hospitals that are part of Dubai Academic Health Corporation.</p><p><strong>Results: </strong>A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n = 13, 57%). The in-hospital mortality rate was 38% (n = 5) in adults and 20% (n = 2) in pediatrics.</p><p><strong>Conclusions: </strong>E. meningoseptica is a significant nosocomial pathogen with high antibiotic resistance, posing severe risks to immunocompromised pediatric and adult patients. Effective management of E. meningoseptica requires vigilant monitoring, comprehensive control, and targeted therapies.</p>\",\"PeriodicalId\":7621,\"journal\":{\"name\":\"American journal of infection control\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2024-10-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"American journal of infection control\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1016/j.ajic.2024.10.016\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"American journal of infection control","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1016/j.ajic.2024.10.016","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}
Elizabethkingia meningoseptica in Dubai, United Arab Emirates: A 7-year multicenter study.
Background: Elizabethkingia meningoseptica (E. meningoseptica) is a gram-negative bacillus. Widely distributed in nature, it poses a significant threat as a nosocomial pathogen, particularly affecting immunocompromised neonates and the elderly.
Methods: This study aimed to describe the antimicrobial susceptibility and outcomes of E. meningoseptica infections over seven years in United Arab Emirates. A retrospective chart review study was conducted at four hospitals that are part of Dubai Academic Health Corporation.
Results: A total of 23 cases were observed during the study, 21 (91%) of which exhibited multidrug resistance. More than half of the cases required intensive care and mechanical ventilation (n = 13, 57%). The in-hospital mortality rate was 38% (n = 5) in adults and 20% (n = 2) in pediatrics.
Conclusions: E. meningoseptica is a significant nosocomial pathogen with high antibiotic resistance, posing severe risks to immunocompromised pediatric and adult patients. Effective management of E. meningoseptica requires vigilant monitoring, comprehensive control, and targeted therapies.
期刊介绍：
AJIC covers key topics and issues in infection control and epidemiology. Infection control professionals, including physicians, nurses, and epidemiologists, rely on AJIC for peer-reviewed articles covering clinical topics as well as original research. As the official publication of the Association for Professionals in Infection Control and Epidemiology (APIC)
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