卷曲的 TLS 是 HCC 消退的先兆

IF 27.7 1区医学 Q1 IMMUNOLOGY

Nature Immunology Pub Date : 2024-10-25 DOI:10.1038/s41590-024-01990-y

Xin Liu, Dan G. Duda

引用次数: 0

摘要

三级淋巴结构（TLS）在人类肿瘤中具有不同的阶段和细胞组成。新数据显示了新辅助免疫疗法对治疗反应性肝癌和治疗耐药性肝癌三级淋巴结构命运的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Involuted TLS as a harbinger of HCC regression

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Involuted TLS as a harbinger of HCC regression

Tertiary lymphoid structures (TLS) have different stages and cellular compositions in human tumors. New data are showing the effect of neoadjuvant immunotherapy on the fate of TLS in treatment-responsive versus treatment-resistant liver cancers.

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来源期刊

Nature Immunology 医学-免疫学

CiteScore

40.00

自引率

2.30%

发文量

248

审稿时长

4-8 weeks

期刊介绍： Nature Immunology is a monthly journal that publishes the highest quality research in all areas of immunology. The editorial decisions are made by a team of full-time professional editors. The journal prioritizes work that provides translational and/or fundamental insight into the workings of the immune system. It covers a wide range of topics including innate immunity and inflammation, development, immune receptors, signaling and apoptosis, antigen presentation, gene regulation and recombination, cellular and systemic immunity, vaccines, immune tolerance, autoimmunity, tumor immunology, and microbial immunopathology. In addition to publishing significant original research, Nature Immunology also includes comments, News and Views, research highlights, matters arising from readers, and reviews of the literature. The journal serves as a major conduit of top-quality information for the immunology community.