{"title":"单侧多睾症伴严重男性不育:病例报告。","authors":"Fang Yang, Jingyi Zhang, Yao Xiao, Shiyun Pu, Meijing Wang, Shengxi Xiong, Xinyi Tang, Xujun Yu, Degui Chang","doi":"10.1186/s12894-024-01626-1","DOIUrl":null,"url":null,"abstract":"<p><p>Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient's sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.</p>","PeriodicalId":9285,"journal":{"name":"BMC Urology","volume":"24 1","pages":"228"},"PeriodicalIF":1.7000,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488241/pdf/","citationCount":"0","resultStr":"{\"title\":\"Unilateral polyorchidism with severe male infertility: a case report.\",\"authors\":\"Fang Yang, Jingyi Zhang, Yao Xiao, Shiyun Pu, Meijing Wang, Shengxi Xiong, Xinyi Tang, Xujun Yu, Degui Chang\",\"doi\":\"10.1186/s12894-024-01626-1\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient's sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.</p>\",\"PeriodicalId\":9285,\"journal\":{\"name\":\"BMC Urology\",\"volume\":\"24 1\",\"pages\":\"228\"},\"PeriodicalIF\":1.7000,\"publicationDate\":\"2024-10-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488241/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Urology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1186/s12894-024-01626-1\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"UROLOGY & NEPHROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Urology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1186/s12894-024-01626-1","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"UROLOGY & NEPHROLOGY","Score":null,"Total":0}
Unilateral polyorchidism with severe male infertility: a case report.
Polyorchidism is an uncommon congenital condition often discovered incidentally, which may significantly impact male fertility. We present a case of a 34-year-old man with unilateral polyorchidism and associated severe asthenozoospermia and teratozoospermia. Despite normal hormonal levels and no detected genetic anomalies, the patient's sperm showed mitochondrial damage, and his fertility remained compromised after conservative management and assisted reproductive attempts. This case underscores the intricate relationship between polyorchidism and male infertility, highlighting the need for personalized management strategies and further research into its etiology and impact.
期刊介绍:
BMC Urology is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of urological disorders, as well as related molecular genetics, pathophysiology, and epidemiology.
The journal considers manuscripts in the following broad subject-specific sections of urology:
Endourology and technology
Epidemiology and health outcomes
Pediatric urology
Pre-clinical and basic research
Reconstructive urology
Sexual function and fertility
Urological imaging
Urological oncology
Voiding dysfunction
Case reports.