Hirotaka Fukasawa, Mito Yamawaki, Jun Furuya, Kyosuke Omata, Mai Kaneko, Takashi Matsuyama, Hideo Yasuda, Ryuichi Furuya
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引用次数: 0
摘要
导言：缺锌在 HD 患者中非常普遍。另一方面，锌在他们营养状况中的作用仍是未知数：我们进行了一项开放标签随机对照试验。方法：我们进行了一项开放标签随机对照试验，研究(i)血清锌水平与身体组成之间的关系；(ii)补锌对 48 例缺锌型 HD 患者身体组成的影响：结果：血清锌水平与身体脂肪重量有明显相关性（p 结论：血清锌水平与身体脂肪重量有明显相关性：我们的研究结果表明，缺锌对缺锌的 HD 患者的脂肪代谢起着重要作用。
The effects of zinc supplementation on body fat mass in hemodialysis patients: An open-label randomized controlled trial.
Introduction: Zinc deficiency is highly prevalent in HD patients. On the other hand, it remains unknown about the role of zinc in their nutritional status.
Methods: We conducted an open-label randomized controlled trial. We investigated (i) the relationship between serum zinc levels and body composition and (ii) the effects of zinc supplementation on the composition of 48 HD patients with zinc deficiency.
Results: Serum zinc levels were significantly correlated with body fat weight (p < 0.01), but not with nonfat tissue weight. Multiple regression analyses demonstrated that serum zinc levels were a significant independent predictor of body fat weight (p < 0.001). Furthermore, the weight of body fat significantly increased in the group that received 1-year zinc supplementation (p < 0.05), but not in the group that did not.
Conclusion: Our findings indicate that zinc deficiency plays an important role in fat metabolism in HD patients with its deficiency.
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