通过传统风险评估或冠状动脉钙化评分进行心血管筛查对健康相关生活质量的短期影响:ROBINSCA 试验。

European heart journal open Pub Date : 2024-09-23 eCollection Date: 2024-09-01 DOI:10.1093/ehjopen/oeae080
Dana Moldovanu, Harry J de Koning, Marleen Vonder, Jan Willem C Gratama, Henk J Adriaansen, Jeanine E Roeters van Lennep, Rozemarijn Vliegenthart, Pim van der Harst, Richard L Braam, Paul R M van Dijkman, Matthijs Oudkerk, Carlijn M van der Aalst
{"title":"通过传统风险评估或冠状动脉钙化评分进行心血管筛查对健康相关生活质量的短期影响:ROBINSCA 试验。","authors":"Dana Moldovanu, Harry J de Koning, Marleen Vonder, Jan Willem C Gratama, Henk J Adriaansen, Jeanine E Roeters van Lennep, Rozemarijn Vliegenthart, Pim van der Harst, Richard L Braam, Paul R M van Dijkman, Matthijs Oudkerk, Carlijn M van der Aalst","doi":"10.1093/ehjopen/oeae080","DOIUrl":null,"url":null,"abstract":"<p><strong>Aims: </strong>Evidence on the impact of screening for cardiovascular diseases (CVDs) on health-related quality of life (HRQoL) is important for policy decisions about screening implementation and to uncover teachable moments to motivate healthy lifestyle choices. It is unknown whether screening by cardiac computed tomography (CT) scan has a stronger impact on HRQoL than screening by traditional risk prediction models. The study aims to investigate differences in HRQoL across the screening process between participants who were randomized to CVD risk estimation by coronary artery calcium score or Systematic COronary Risk Evaluation.</p><p><strong>Methods and results: </strong>A subset of 2687 ROBINSCA participants filled in questionnaires at (T0) randomization, (T1) invitation, (T2) 1-3 days before screening, (T3) 1-3 days after, and (T4) screening result. Generic HRQoL (SF-12; EQ-5D) and anxiety (STAI-6) were measured. We investigated the differences in changes in HRQoL across the screening process with linear mixed models. We found comparable levels of HRQoL at all screening moments for the two intervention groups. Mental health scores were worse at invitation and randomization than at the later time points, irrespective of screening group (all <i>P</i> < 0.001). A result indicating a heightened CVD risk was associated with increased anxiety in the CT screening group.</p><p><strong>Conclusion: </strong>Computed tomography screening for CVD risk has no detrimental impact on HRQoL and anxiety levels compared to screening by traditional risk assessment. Receiving an invitation to screenning or a result implying increased CVD risk could function as teachable moments for high-risk individuals.</p><p><strong>Registration: </strong>ROBINSCA trial registration number: NTR6471 in Dutch Trial Register (NTR).</p>","PeriodicalId":93995,"journal":{"name":"European heart journal open","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483572/pdf/","citationCount":"0","resultStr":"{\"title\":\"Short-term impact of cardiovascular screening by traditional risk assessment or coronary artery calcium score on health-related quality of life: the ROBINSCA trial.\",\"authors\":\"Dana Moldovanu, Harry J de Koning, Marleen Vonder, Jan Willem C Gratama, Henk J Adriaansen, Jeanine E Roeters van Lennep, Rozemarijn Vliegenthart, Pim van der Harst, Richard L Braam, Paul R M van Dijkman, Matthijs Oudkerk, Carlijn M van der Aalst\",\"doi\":\"10.1093/ehjopen/oeae080\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aims: </strong>Evidence on the impact of screening for cardiovascular diseases (CVDs) on health-related quality of life (HRQoL) is important for policy decisions about screening implementation and to uncover teachable moments to motivate healthy lifestyle choices. It is unknown whether screening by cardiac computed tomography (CT) scan has a stronger impact on HRQoL than screening by traditional risk prediction models. The study aims to investigate differences in HRQoL across the screening process between participants who were randomized to CVD risk estimation by coronary artery calcium score or Systematic COronary Risk Evaluation.</p><p><strong>Methods and results: </strong>A subset of 2687 ROBINSCA participants filled in questionnaires at (T0) randomization, (T1) invitation, (T2) 1-3 days before screening, (T3) 1-3 days after, and (T4) screening result. Generic HRQoL (SF-12; EQ-5D) and anxiety (STAI-6) were measured. We investigated the differences in changes in HRQoL across the screening process with linear mixed models. We found comparable levels of HRQoL at all screening moments for the two intervention groups. Mental health scores were worse at invitation and randomization than at the later time points, irrespective of screening group (all <i>P</i> < 0.001). A result indicating a heightened CVD risk was associated with increased anxiety in the CT screening group.</p><p><strong>Conclusion: </strong>Computed tomography screening for CVD risk has no detrimental impact on HRQoL and anxiety levels compared to screening by traditional risk assessment. Receiving an invitation to screenning or a result implying increased CVD risk could function as teachable moments for high-risk individuals.</p><p><strong>Registration: </strong>ROBINSCA trial registration number: NTR6471 in Dutch Trial Register (NTR).</p>\",\"PeriodicalId\":93995,\"journal\":{\"name\":\"European heart journal open\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-09-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483572/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European heart journal open\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/ehjopen/oeae080\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/9/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European heart journal open","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/ehjopen/oeae080","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/9/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

目的:有关心血管疾病(CVD)筛查对健康相关生活质量(HRQoL)影响的证据对于筛查实施的政策决策以及发现激励人们选择健康生活方式的教学时机非常重要。目前尚不清楚心脏计算机断层扫描(CT)筛查是否比传统风险预测模型筛查对 HRQoL 有更大的影响。本研究旨在调查通过冠状动脉钙化评分或系统性冠状动脉风险评估进行心血管疾病风险评估的随机参与者在整个筛查过程中的 HRQoL 差异:2687名ROBINSCA参与者在随机化(T0)、邀请(T1)、筛查前1-3天(T2)、筛查后1-3天(T3)和筛查结果(T4)时填写了问卷。对一般 HRQoL(SF-12;EQ-5D)和焦虑(STAI-6)进行了测量。我们使用线性混合模型研究了整个筛查过程中 HRQoL 变化的差异。我们发现,两个干预组在所有筛查时刻的 HRQoL 水平相当。无论筛查组别如何,受邀和随机时的心理健康评分都比之后的时间点要差(所有 P <0.001)。CT筛查组的结果表明心血管疾病风险增加与焦虑增加有关:结论:与传统的风险评估筛查相比,计算机断层扫描心血管疾病风险筛查不会对患者的心身健康质量和焦虑水平产生不利影响。收到筛查邀请或筛查结果意味着心血管疾病风险增加,这对高危人群来说是一个可教的时刻:ROBINSCA试验注册号:NTR6471注册:ROBINSCA 试验注册号:NTR6471,荷兰试验注册(NTR)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Short-term impact of cardiovascular screening by traditional risk assessment or coronary artery calcium score on health-related quality of life: the ROBINSCA trial.

Aims: Evidence on the impact of screening for cardiovascular diseases (CVDs) on health-related quality of life (HRQoL) is important for policy decisions about screening implementation and to uncover teachable moments to motivate healthy lifestyle choices. It is unknown whether screening by cardiac computed tomography (CT) scan has a stronger impact on HRQoL than screening by traditional risk prediction models. The study aims to investigate differences in HRQoL across the screening process between participants who were randomized to CVD risk estimation by coronary artery calcium score or Systematic COronary Risk Evaluation.

Methods and results: A subset of 2687 ROBINSCA participants filled in questionnaires at (T0) randomization, (T1) invitation, (T2) 1-3 days before screening, (T3) 1-3 days after, and (T4) screening result. Generic HRQoL (SF-12; EQ-5D) and anxiety (STAI-6) were measured. We investigated the differences in changes in HRQoL across the screening process with linear mixed models. We found comparable levels of HRQoL at all screening moments for the two intervention groups. Mental health scores were worse at invitation and randomization than at the later time points, irrespective of screening group (all P < 0.001). A result indicating a heightened CVD risk was associated with increased anxiety in the CT screening group.

Conclusion: Computed tomography screening for CVD risk has no detrimental impact on HRQoL and anxiety levels compared to screening by traditional risk assessment. Receiving an invitation to screenning or a result implying increased CVD risk could function as teachable moments for high-risk individuals.

Registration: ROBINSCA trial registration number: NTR6471 in Dutch Trial Register (NTR).

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
2.80
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信